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PubMed · 11387669

[Cryptococcosis].

F Dromer
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Abstract

Cryptococcus neoformans, an encapsulated yeast is responsible for life-threatening infection in patients with cellular immune defect especially those with AIDS. The most frequent presentation of cryptococcosis is a disseminated meningoencephalitis without acute onset. The diagnosis is based on direct examination with India ink staining, detection of soluble capsular polysaccharide in body fluids, culture of the micro-organism or histology. Looking for other localisations and for factors of poor prognosis is mandatory before selecting the right treatment regimen. In case of meningitis, one should prefer a combination of amphotericin B and 5 fluorocytosin, followed by a triazole, usually fluconazole until sterilisation of all infected sites is achieved or even for life-time maintenance therapy in case of sustained immune defect.

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AIDS-Related Opportunistic InfectionsAdultAmphotericin BAntifungal AgentsChildCryptococcosisFemaleFlucytosineHumansMaleMeningitis, CryptococcalMycologyPrognosisRisk FactorsTime FactorsEnglish AbstractJournal ArticleReview

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F Dromer. 2001-04-15. [Cryptococcosis].. https://pubmed.ncbi.nlm.nih.gov/11387669/

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