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PubMed · 10971106

Hypophosphataemic rickets.

G Saggese·G I Baroncelli
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Abstract

X-Linked hypophosphataemic rickets (XLH) is frequently associated with short stature even when conventional treatment (1, 25-dihydroxyvitamin D(3) or 1alpha-hydroxyvitamin D(3) plus inorganic phosphate salts) is administered for a long time. The pathogenesis of growth retardation is probably multifactorial. Affected patients usually show normal growth hormone (GH) secretion. In some poorly growing XLH patients, long-term GH treatment associated with conventional therapy improves linear growth. GH treatment also increases phosphate retention but this effect is transient.

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ChildGrowthHuman Growth HormoneHumansHypophosphatemia, FamilialJournal ArticleReview

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BibTeXRIS

G Saggese, G I Baroncelli. 2000. Hypophosphataemic rickets.. https://doi.org/10.1159/000023535

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