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PubMed · 10963478

Epilepsy surgery in developing countries.

P D Williamson·B C Jobst
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Abstract

Epilepsy surgery (ES) is a well-accepted treatment for medically intractable epilepsy patients in developed countries, but it is highly technology dependent. Such technology is not usually available in developing countries. For presurgical evaluation, magnetic resonance imaging (MRI) and electroencephalogram recording while videotaping the patient have been important. High technology equipment will, in conjunction with MRI, identify approximately 70% of ES candidates. Introducing ES into developing countries will require determining the candidates that are appropriate for the existing medical infrastructure. This article reviews ES and its possible introduction into conditions existing in developing countries. The authors address (a) the types of patients to be considered for resective ES (some patients require a fairly standard series of noninvasive studies: others will require extensive invasive studies), (b) ways to determine which patients might be appropriate for the existing situation (unilateral mesial temporal lobe epilepsy detected with MRI, epilepsy with a circumscribed MRI lesion, hemispheric lesions, circumscribed MRI detected neuronal migration, and development disorders), (c) surgical procedures (local resection, functional hemispherectomy, multiple subpial transections, corpus callosotomy, and implantation of a vagal nerve stimulator), (d) special considerations for introducing ES into developing countries (medical infrastructure, technology, seizure monitoring systems, selective intracarotid/carotid Amytal testing, and surgical equipment), and (e) the limitations, realistic expectations, personnel requirements, and educational function for selected professionals. Delivery of the technology and expertise to perform ES in developing regions of the world is a realizable project, but it would be limited by available technology and existing medical infrastructure. It should be possible in most areas to train local personnel and thereby leave a lasting legacy.

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Cerebral CortexDelivery of Health CareDeveloping CountriesElectric Stimulation TherapyElectroencephalographyEpilepsyEpilepsy, Temporal LobeFinancing, OrganizedHumansMagnetic Resonance ImagingMedical Laboratory ScienceNeurologyNeurosurgeryPatient SelectionTemporal LobeVagus NerveJournal ArticleReview

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BibTeXRIS

P D Williamson, B C Jobst. 2000. Epilepsy surgery in developing countries.. https://doi.org/10.1111/j.1528-1157.2000.tb01546.x

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