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PubMed · 10877696

Development. PARallels in axis formation.

J Morris·R Lehmann·C Navarro
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Abstract

There is an intricate network of molecules called cell fate determinants that instruct the cells of the embryo to take on either an anterior or posterior fate. In a lively Perspective, Lehmann and her colleagues discuss new findings in the fruit fly that identify a key protein, PAR-1, which ensures that the cell fate determinants are themselves located in the correct region of the oocyte. In this way, the anterior-posterior axis is set up in the fruit fly egg before fertilization.

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Actin CytoskeletonAnimalsBody PatterningCaenorhabditis elegansCell PolarityCentrosomeDrosophilaDrosophila ProteinsHomeodomain ProteinsInsect ProteinsMicrotubulesMutationOocytesProtein Serine-Threonine KinasesRNA, MessengerRNA-Binding ProteinsSignal TransductionTrans-ActivatorsJournal Article

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J Morris, R Lehmann, C Navarro. 2000-06-09. Development. PARallels in axis formation.. https://doi.org/10.1126/science.288.5472.1759

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