[Thyrotropia].

Abstract

The significance of the radioimmunological dosage of the thyrotropic hormone (TSH) is examined as regards accordance between the experimental measure and the real behaviour of the hormone; as a matter of fact, in some particular conditions the problem of the specificity of dosage must be taken into account because of the possible interference of other hormones. From the clinical point of view the TSH radioimmuno assay is advisable for its accuracy, sensibility and specificity. On the other other hand, it is a lengthy and complex determination; instability of the labelled hormone is to be pointed out as the worst shortcoming. The procedures for clinical study of TSH are also examined with reference to an indirect evaluation of the thyroid function. tthe clinical application of TSH dosage in endrocrinology diagnostics, concerning both thyroid and hypophysis pathology, are discussed.