Figuring it out.

This Review covers the delineation and optimization of protein-lipid systems for study using solution-state NMR spectroscopy. The first half presents the necessary background for a membrane protein biochemist to initiate collaboration with an NMR spectroscopist. The second half provides guidelines for the spectroscopist on data collection, analysis for obtaining conformational information, and structure generation and assessment. Although the emphasis is on the study of peptides in detergent micelles, methods are outlined for larger membrane-associated proteins and for use of other solubilizing agents.

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PubMed2001

The complementarity of phenomenology, hermeneutics and existentialism as a philosophical perspective for nursing research.

The focus of this paper draws on the thinking of Husserl, Dilthey and Heidegger to identify elements of the phenomenological movement that can provide focus and direction for qualitative research in nursing. The authors interpret this tradition in two ways: emphasizing the possible complementarity of phenomenology, hermeneutics and existentialism, and demonstrating how these emphases ask for grounding, reflexivity and humanization in qualitative research. The paper shows that the themes of grounding, reflexivity and humanization are particularly important for nursing research.

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PubMed2001

Use of the Internet by medical voluntary groups in the UK.

Voluntary organisations and charities established as self-help groups are contributing to the democratisation of health-related information. As part of the Internet revolution in communication, such organisations are developing web sites. This short report surveyed all UK voluntary groups in the field of neurology. Of these, 71% had a web site, while the Internet was also used for research, advertising, fund raising and to host a discussion forum. These findings are discussed in terms of the quality of information available to people using the Internet.

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