PubMed · 10243484
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G L Briese. 1979. Elevator extrication.. https://pubmed.ncbi.nlm.nih.gov/10243484/
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OBJECTIVE: To investigate the association between cholesterol lowering interventions and risk of death from suicide, accident, or trauma (non-illness mortality). DESIGN: Meta-analysis of the non-illness mortality outcomes of large, randomised clinical trials of cholesterol lowering treatments. STUDIES REVIEWED: 19 out of 21 eligible trials that had data available on non-illness mortality. INTERVENTIONS REVIEWED: Dietary modification, drug treatment, or partial ileal bypass surgery for 1-10 years. MAIN OUTCOME MEASURE: Deaths from suicides, accidents, and violence in treatment groups compared with control groups. RESULTS: Across all trials, the odds ratio of non-illness mortality in the treated groups, relative to control groups, was 1.18 (95% confidence interval 0.91 to 1.52; P=0.20). The odds ratios were 1.28 (0.94 to 1.74; P=0.12) for primary prevention trials and 1.00 (0.65 to 1.55; P=0.98) for secondary prevention trials. Randomised clinical trials using statins did not show a treatment related rise in non-illness mortality (0.84, 0.50 to 1.41; P=0.50), whereas a trend toward increased deaths from suicide and violence was observed in trials of dietary interventions and non-statin drugs (1.32, 0.98 to 1.77; P=0.06). No relation was found between the magnitude of cholesterol reduction and non-illness mortality (P=0.23). CONCLUSION: Currently available evidence does not indicate that non-illness mortality is increased significantly by cholesterol lowering treatments. A modest increase may occur with dietary interventions and non-statin drugs.
BACKGROUND: Little is known about suicide in England in the medieval period. Legal records provide the best source of post-mortem data about suicides. METHOD: Selected Eyre records from the reigns of Henry III (1216-1272), Edward I (1272-1307), Edward II (1307-1327) and Edward III (1327-1377) were translated and examined for details of self-killing. RESULTS: One hundred and ninety-eight cases of self-killing were found, eight of which were found to be accidental, non-felonious deaths. Self-killing was more common in men. Hanging was the most common and drowning the second most common method of self-killing in both males and females. Self-killing with sharp objects was predominantly a male method. Other methods of self-killing were rare. There were no reports of deliberate self-poisoning. There is some evidence of underreporting of, and attempts to conceal, self-killing from royal officers. CONCLUSIONS: Eyre records suggest that although some of the facts surrounding self-killing have changed, others have remained constant, particularly the higher proportion of men who kill themselves and the greater use by men than women of sharp instruments to kill themselves. We discuss the description and understanding of psychiatric states by medieval English Eyres, particularly in terms of the perception of the mental states that accompanied suicidal actions.
Methamphetamine, a central nervous system stimulant, is manufactured in illicit laboratories using over-the-counter ingredients. Many of these ingredients are hazardous substances that when released from active or abandoned methamphetamine laboratories can place first responders at risk for serious injuries and death. In 16 states, the Agency for Toxic Substances and Disease Registry maintains the Hazardous Substances Emergency Events Surveillance (HSEES) system to collect and analyze data about the morbidity and mortality associated with hazardous substance-release events. Based on events reported to HSEES during 1996-1999, this report describes examples of events associated with illicit methamphetamine laboratories that resulted in injuries to first responders in three states, summarizes methamphetamine-laboratory events involving injured first responders, and suggests injury prevention methods to protect first responders.