PubMed · 10236171
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B A Rowley. Testing pacemakers.. https://pubmed.ncbi.nlm.nih.gov/10236171/
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The ions of solutions exposed to the propagation of ultrasound in the presence of a magnetic field experience Lorentz force. Their movement gives rise to a local electric current density, which is proportional to the electric conductivity of the medium. In vitro assessment of this current is performed using simple models of biological media. A constant magnetic field of 0.35 T and 500 kHz pulsed ultrasound are used. The sensing electrodes are exposed to neither the pressure wave nor the magnetic field, thus ensuring that the signal is not due to any undesirable electrode effect. The experimental results confirm that the current is proportional to the electrical conductivity of the medium. The changes in the measured current against the width of the measurement chamber show that the electrodes only collect a fraction of the current created within the medium. The magnitude of the measured current is 50nA in a saline solution of 0.5 S/m conductivity. The technique enabled the determination of the conductivity of a porcine blood sample against haematocrit. It is concluded that this type of measurement has the potential to allow the electrical conductivity of a medium to be determined using ultrasound.
The myelin sheath is normally regarded as an electrical insulator. Low values of radial conductance and capacitance have been measured, and in electrical models of myelinated axons the contribution of longitudinal conduction within the sheath has been ignored. According to X-ray diffraction studies, however, myelin sheaths comprise alternate lipid and aqueous layers, and the latter may be expected to have a low resistivity. We propose a new model of myelinated axons in which the aqueous layers within the myelin provide appreciable longitudinal and radial conductance, the latter via a spiral pathway. We have investigated the likely contribution of these conductive paths within the myelin to the electrical properties of a human motor nerve fibre by computer simulation, representing the myelin sheath as a series of interconnecting parallel lamellae. With this new model, action potential conduction has been simulated along a 20-node cable, and the electrotonic responses to 100-ms depolarizing and hyperpolarizing current pulses have been simulated for a uniformly polarized fibre. We have found that the hypothesis of a longitudinally conducting myelin sheath improves our previous model in two ways: it is no longer necessary to make implausible assumptions about the resistivity or width of the periaxonal space to simulate realistic electrotonus, and the conduction velocity is appreciably faster (by 8.6%).
An investigation program for monitoring pyrite oxidation on a conveyer bridge dump used geoelectric measurement for monitoring the progress of pyrite oxidation within the dump. The results of the geoelectric measurement show that low soil-pH and high pore water conductivity correlate with low soil resistivity values. The soil resistivity values are dominated by high pore water conductivity. The influence of changes in water saturation on resistivity was comparably low. An increase in pyrite oxidation was observed in areas with high porosity due to low dump density. Consecutive geoelectric measurements revealed locally differentiated downward movement of an oxidation zone caused by dump heterogeneity.