Enzymatic methods for mutation scanning.

G R Taylor; J Deeble

doi:10.1016/s1050-3862(98)00029-1

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Enzymatic methods for mutation scanning.

G R Taylor·J Deeble

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Abstract

Enzymatic methods for mutation scanning still lack the sensitivity and specificity of the chemical cleavage of mismatch method. However developments in our understanding of the mismatch recognition process should lead to improvements. Several promising candidates exist with potential for more specific and sensitive mutation detection.

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Adenosine Triphosphatases Bacterial Proteins DNA Glycosylases DNA Mutational Analysis DNA-Binding Proteins Endodeoxyribonucleases Escherichia coli Proteins MutS DNA Mismatch-Binding Protein N-Glycosyl Hydrolases Ribonucleases Sensitivity and Specificity Single-Strand Specific DNA and RNA Endonucleases Comparative Study Journal Article Review

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G R Taylor, J Deeble. 1999. Enzymatic methods for mutation scanning.. https://doi.org/10.1016/s1050-3862(98)00029-1

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