Biomedical subjects
Publications and source records attributed to Z Zhao.
Based on the method of assessing the growing age of trees by "annual ring in the bark", the active ingredients magnolol and honokiol in 3 species Houpo (Magnolia officinalis, M. biloba, M. rostrata) of different ages, were determined by HPLC. The results present a reference for defining the reasonable period of collection and quality evaluation of Houpo.
The study adopts circular distribution method and periodic regression technology with cosine curve to make statistic analysis. According to the result of the statistic by season, among 4,636 babies of natural parturition from 1985 to 1988, the angle even value is 272.91 degrees, a = 0.05, by evenness examination, which indicates the tendency of concentration. The further periodic regression analysis gives out an equation: ŷ = 289.75 + 48.68 cos (wti-272.91), determination coefficient R2 = 0.56, and variance analysis concludes F = 8.35, P less than 0.01. The fitting result is satisfied, which points out that the birth time season waves in a year's period and the birth rate is high in winter. While the statistic by month, the angle even value is 338.40 degrees, a = 0.01, ŷ = 96.58 + 19.82 cos (wti-338.40), R2 = 0.42, F = 15.28, P less than 0.01, which still indicate that the birth time has a year's periodic fluctuation, with its peak on December 8. As for the statistic by day in each month, the angle even value is 213.86 degrees, evenness examination P greater than 0.05, indicating no monthly periodic fluctuation and no peak on 1st and 15th of lunar year, while the statistic by birth o'clock in a day, the angle even value is 117.31 degrees, P greater than 0.05, no day and night rhythm.
Explore the source record for details and available documents.
The preferential binding of 1-anilinonaphthalene-8-sulfonate by rabbit muscle phosphorylase a is the basis of a continuous fluorometric assay for phosphorylase kinase. The maximum rate of change in fluorescence (d delta F/dt) is dependent on both the concentration of phosphorylase kinase and on conditions, such as pH and calcium ion concentration, which affect the enzyme. Parallel measurements of the increases in fluorescence and of 32P incorporation demonstrate the existence of a distinct intermediate in the conversion of phosphorylase b to a. We have used the assay to monitor the increase in calcium-independent activity which accompanies the limited chymotryptic digestion of phosphorylase kinase.
A three-stage stochastic epidemic model extending the so-called classical epidemic process to one that includes time-dependent transition probabilities is described, and a solution to the appropriate set of forward differential-difference equations is given. When an individual can move from being a susceptible to one infected with the HIV virus to one diagnosed as having AIDS, we can use this general model to describe an AIDS epidemic process. We obtain expressions for the mean and variance of the number of AIDS cases for some special cases. By comparing these with actual data, it is suggested that, for some categories of cases (in particular, children), this model might be a plausible model to describe the underlying mechanism of the AIDS epidemic.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
This paper reports a method for determining tetramethyl pyrazine in pilules, injections and extracts of Ligusticum chuanxiong by high performance liquid chromatography. The results showed the recovery rate to be higher than 97% and the coefficient of variation (CV) to be 1.39% (with in day) and 1.51% (day to day). The lowest detection amount was 0.005 micrograms. The method was easy, fast and accurate.
Traditional experience calls for the skinning of Radix Adenophorae. Depending on the chemical compositions, this paper presents a comparative study on the skin, the radix with skin and the skinned radix. The experimental results show that the contents of beta-sitosterol, saponins, amino acids and trace elements are highest in the radix with skin, and that the radix with skin and the skinned radix are similar in the contents of polysaccharides.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The effect of light on the abundance of beta-tubulin mRNA was measured in etiolated Avena sativa L. and Hordeum vulgare L. seedlings. Slot blot analysis employing an oat beta-tubulin cDNA clone was used to measure beta-tubulin mRNA levels. White light induced a 45% decrease in oat beta-tubulin mRNA abundance by 2 hours after transfer. A saturating red light pulse induced 40 and 55% decreases in beta-tubulin mRNA levels in oats and barley, respectively. Recovery of beta-tubulin mRNA levels was observed after a red light pulse but not after transfer to continuous white light. The red light induced decrease in oat beta-tubulin mRNA abundance was not reversible by a subsequent far-red light treatment. The mesocotyl portion of etiolated oat seedlings exhibited a more dramatic decrease in beta-tubulin mRNA abundance in response to red light than did the coleoptile portion. The results indicate that the well-documented effects of red light on the growth of etiolated seedlings are accompanied by changes in the expression of the beta-tubulin genes.
This paper reports the determination methods for calcium carbonate, trace elements and amino acids in the traditional Chinese medicine Os Sepiae. The data provide a reference for the quality control of the drug.
We examined the effect of tetrandrine on platelet aggregation, platelet adhesion and coagulation in vitro. The results showed that tetrandrine markedly inhibited the platelet aggregation induced by ADP or collagen. Tetrandrine also markedly inhibited platelet adhesion and thrombosis, but didn't change thrombin coagulation time and plasma coagulation time obviously.
Species of P. pseudomallei can be classified into two serotypes, serotype I and serotype II, based on whether or not it contains a thermolabile antigen beside a thermostable one. Under the condition of lack of typing serum, by means of serum absorption test, we recognized a strain which contains a major thermolabile antigen. The antigen was purified by Sephadex G-200, and it was used to inoculate rabbits. With the immunoserum at hand, we identified 68 of the domestic chinese strains and 6 of alien strains for serotyping by bi-directional agar diffusion test. The results showed that 68 strains were identified serotype I, 3 strains serotype II, and the remaining 3 comparable with those reported indicating that strains of serotype I were found mostly in Asia, and that the serotype are unrelated to their existing environments, nor that of animal bodies, but connected with their existence in geographic distribution.
Explore the source record for details and available documents.
Explore the source record for details and available documents.