Biomedical subjects

Z X Wu

Publications and source records attributed to Z X Wu.

31 records · Page 2Linked to original sources

PubMed1993

The use of dot-immunogold-silver staining (dot-IGSS), dot-ELISA and dot-IGSS to detect serum antibodies from clonorchiasis patients: a comparative study.

We report the use of immunogold-silver staining (IGSS), dot-ELISA and dot-IGSS methods in the study of clonorchiasis in China. These methods were employed to detect the antibody in sera from 40 clonorchiasis patients. The positive rates were 100%, 90.0% and 95.0%, respectively. When the three methods were used to examine 40 normal sera, the negative rates were 100%, 97.5% and 97.5%, respectively. These results suggest that IGSS, dot-ELISA and dot-IGSS are highly specific and sensitive in detecting anti-Clonorchis antibody in patients.

Antibodies, Helminth↗

PubMed1993

[Embolization treatment of carotid-cavernous fistula with balloon catheter].

Fifty-five cases of carotid-cavernous fistula (CCF) were treated with detachable balloon catheter from Oct. 1986 to Aug. 1992. Of these cases, 52 were embolized successfully with patented carotid arteries in 36. The clinical data, neurological complications and embolization methods were evaluated. We believe that intravascular embolization is the best method for treating CCF.

Adolescent↗

PubMed1993

[Intravascular embolization in treatment of craniocerebral vascular diseases].

From Aug. 1986 to June 1992, 193 cases of craniocerebral vascular diseases were treated with intravascular embolization. Among these there were 52 cases of carotid-cavernous fistula (CCF), 31 intracranial aneurysms, 83 arteriovenous malformations (AVM), and 27 dural AVMs. Intravascular embolization was first used in the treatment of CCF and dural AVM. For those of non-clippable aneurysms, detachable balloon catheter was adopted, but investigation of whole brain vessels and Matas' test should be made before embolization. As to brain AVM, embolization or combination of embolization and surgery is practical in some cases. Use of IBCA glue or silk suture in embolization is depends on the anatomical feature of AVM.

Adolescent↗

PubMed1990

Treatment of traumatic carotid-cavernous fistula with detachable balloon.

From November 1986 to February 1989, 18 patients with traumatic carotid-cavernous fistulas were treated by means of detachable balloon, which was made by ourselves. Successful embolization was achieved in 15 patients. Draining features of the fistulas and methods of embolization were introduced. The method was compared with other methods. Selection of treatments and problems in embolization are discussed.

Adult↗

PubMed1990

[Clinical observations on the treatment of hookworm, Ascaris and Trichuris infection with oxibendazole].

340 cases of hookworm infection, 196 cases of ascariasis and 178 cases of trichuriasis were treated with an anthelmintic, oxibendazole, 15mg/kg.d x 3d; 102, 70 and 66 cases of respective infections were treated with pyrantel 10mg/kg.d x 3d and 108, 74 and 63 cases took placebo for comparison and as control under double-blind observations. Re-examinations of the stool were performed after the treatment. Among the cases treated with oxibendazole, the egg negative conversion rates of hookworm, Ascaris and Trichuris were 70.3-80.6%, 92.5-97.8 and 67.0-71.0% respectively. The egg reduction rates of hookworm were 98.1-98.6%. The larval negative conversion rates of Ancylostoma duodenale and Necator americanus were 77.7 and 83.2% respectively. Among the cases treated with pyrantel, the egg negative conversion rates of the three above mentioned parasites were 73.5, 90.0 and 28.8% respectively. The egg reduction rate of hookworm was 98.8%. Among the cases treated with placebo, the egg negative conversion rates of the three above mentioned parasites were 6.5, 29.7 and 7.9%. No marked adverse reactions were observed by clinical and laboratory examinations.

Animals↗

PubMed1989

[The effects of longterm selection on the genetic structure of populations--a simulation study. II. The effects of selection on genetic variances].

Monte Carlo simulation has been done to study the effects of longterm artificial selection on genetic variances under additive, dominant, and over-dominant models. The effects of population size, linkage, and heritability have been considered. Just as under the additive model, the additive variance under the dominant and over-dominant models has also been decomposed into three components which represent changes in gene frequencies (VT), departure from Hardy-Weinberg equilibrium (VHW) and from linkage equilibrium (VLD) respectively. These present a resonable approach to study the association among multiple genes. In small populations, genetic variance fluctuates wildly over generations and replicates due to the establishment of linkage disequilibrium. Rapid decrease of VT observed. Intense linkage retained a greater additive variance in the small populations while slowing down responses, which makes it difficult to predict responses during longterm selection.

Animals↗

PubMed1989

[Effects of longterm selection on the genetic structure of populations--a simulation study. I. Simulation models and selection responses].

Monte Carlo method has been utilized to investigate responses to longterm selection. The simulation involves 3 gene effect models (additive, dominant, and over-dominant), two population sizes, three linkage intensities, and three heritability levels, thus making 54 combinations. For each combination, 5 replicate populations are selected over 49 consecutive non-overlapping generations. The results demonstrate that under all the gene effect models, linkage is important only in the case of small populations and intense linkage, when it reduces responses significantly due to hampering the fixation of favourable alleles and accelerating their loss. Linkage has no apparent effect if it is not very tight or if the population is large. Much greater responses are achieved in the large populations than in the small ones, especially for traits with low heritability. Among those discussed are problems of crossing selected lines to obtain extra responses, and discrepancy of some theoretic results on selection limits.

Computer Simulation↗

PubMed1988