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Biomedical subjects

Z Vogel

Publications and source records attributed to Z Vogel.

123 records · Page 7Linked to original sources
PubMed1973

Development of acetylcholine receptor clusters on cultured muscle cells.

Clusters of acetylcholine receptors were formed in the absence of neurons during the development of cultured chick-embryo skeletal muscle cells. The average concentration of receptors in clusters was estimated to be 9000 per mum(2). At other regions of the cell, receptor concentration was 900 per mum(2). The possibility that receptor clusters may participate in synapse formation is suggested.

Animals↗
PubMed1972

Acetylcholine receptors of muscle grown in vitro.

[(125)I]Monoiodo- and [(125)I]diiodo-alpha-bungarotoxin were synthesized and shown to bind specifically to the acetylcholine receptor of cultured embryonic chick- and rat-muscle cells. The pharmacologic properties of the receptor of cultured embryonic chick muscle resembled those of the nicotinic acetylcholine receptor of adult vertebrate muscle. Autoradiography of muscle cells labeled with toxin showed that acetylcholine receptors were distributed over the entire cell surface. In addition, discrete areas with a high receptor concentration were found.

Acetylcholine↗