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Biomedical subjects

Z Rybicki

Publications and source records attributed to Z Rybicki.

18 recordsLinked to original sources
PubMed2001

[Problems with infections during the perioperative period].

The paper addresses issues related to the prophylactic and empirical use of antibiotics in surgery. Apart from the factors related to post-operation infections, it presents recommendations and proposals for the prophylactic use of antibiotics in particular types of operations. The recommendations are based on the American and European specialist literature, with the differences between these two approaches clearly outlined. Additional comments are provided for the important elements of prophylactics in particular types of operations. In the part concerning the use of antibiotics in treatment of intra-abdominal infections, the focus is on the general rules for antibiotherapy in pancreatitis. There is also a discussion of mycotic complications accompanying intra-abdominal infections. The paper ends with specific indications for the empirical use of antibiotics in intra-abdominal infections.

Anti-Bacterial Agents↗
PubMed1989

Allogeneic bone marrow transplantation from HLA-identical siblings following conditioning with busulfan and cyclophosphamide. First results.

In the time period from November 1984 to January 1987 eight allogeneic bone marrow transplantation were performed from HLA-identical siblings. The theoretical chance of success in this group was between 21 and 50%, according to the recent data of the International Bone Marrow Transplant Registry, depending on the diagnosis and clinical condition. The average chance was 37.5%. Haemopoietic reconstitution was achieved in 6 recipients, while 2 died of early complications (cytostatic induced hepatocellular damage and fungal sepsis). Another 3 patients died of complications of the intermediate period (pulmonary bleeding, virus hepatitis, graft rejection). The remaining 3 recipients are alive, in excellent clinical condition, including one girl surviving more than 2 years after the transplantation.

Adolescent↗
PubMed1988

[Rejection of allogeneic bone marrow transplant. Case report].

In a patient aged 22 years with acute myeloblastic leukaemia during complete remission an allogenic transplant of bone marrow identical in the HLA antigen range was rejected despite administration before transplantation of a full marrow-ablating dose of busulphan (16 mg/kg) and severe graft-versus-host disease. Graft rejection manifested itself as disappearance of its haemopoietic function which was confirmed during the life and on autopsy. The case deserves attention in view of the rarity of HLA-identical marrow graft rejections in patients treated for leukaemias.

Adult↗
PubMedDate not supplied

Acid-base balance and blood gases changes and "lactate excess" in acute respiratory alkalosis during general anaesthesia.

In 40 young males aged 18-20 years operated on for inguinal hernioplasty acute respiratory alkalosis was obtained in the 45th minute of general anaesthesia. The values of basic acid-base balance parameters, blood gases, pyruvate and lactate levels and "lactate excess" were determined before and after hyperventilation. Shifts in the concentrations of hydrogen and bicarbonate ions were found which are both typical of acute respiratory alkalosis. No changes were observed in the oxygenation of capillary blood and the values of "lactate excess" were normal which rules out tissue hypoxia during acute respiratory alkalosis. Passive hyperventilation being a less dangerous alternative of hypoventilation is a frequent occurrence during general anaesthesia and it causes transient respiratory alkalosis.

Acid-Base Equilibrium↗