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Biomedical subjects

Z R Zunnunov

Publications and source records attributed to Z R Zunnunov.

At least 19 recordsLinked to original sources
PubMed2004

[Efficacy and safety of hydrogen sulfide balneotherapy in ischemic heart disease the arid zone].

AIM: To evaluate efficacy of hydrogen sulfide (HS) balneotherapy in patients with coronary heart disease (CHD) in conditions of heat discomfort. MATERIAL AND METHODS: The study included 72 CHD patients aged 35 to 60 years with stable angina pectoris of the second functional class taking balneotherapy in summer under arid climatic conditions. Before and after balneotherapy the patients were examined with estimation of clinical symptoms, stress bicycle exercise (SBE) parameters, number of nitroglycerine tablets. RESULTS: The balneotherapy resulted in a significant prolongation of SBE (p < 0.0018), in longer time to depression of the ST segment by 1 mm (p < 0.01), to an anginal attack in the course of SBE (p < 0.0036), shorter duration of pain after SBE (p < 0.001), less number of anginal attacks (p < 0.0002) and reduced need in short-acting nitrates (p < 0.0002). CONCLUSION: In a hot climate of the arid zone use of moderate HS baths raises tolerance of CHD patients to exercise, attenuates clinical manifestations of CHD and, consequently, reduces daily need in nitrates.

Adult↗
PubMed2003

[Clinical efficiency and tolerance of hydrogen sulfide balneotherapy in hypertensive patients living in arid zone].

AIM: To examine clinical efficiency and safety of moderate hydrogen sulfide (HS) baths in the treatment of hypertensive patients living in arid zones. MATERIAL AND METHODS: Sixty patients with stable essential hypertension (EH) of stage I-II according to WHO classification living in arid climate took sparing HS baths. Efficiency of the baths was assessed by changes in blood pressure (BP), 24-h monitoring of BP. RESULTS: It is shown that systolic and diastolic BP after HS balneotherapy fell significantly both in daytime and at night. The 24-h profile of BP improved, heart rate decreased by 4.3%, physiological fluctuations of BP and BP variability were not damaged. CONCLUSION: Moderate HS baths are recommended for wider use in a hot climate of the arid zone as an effective and safe method of balneotherapy which can be adjuvant to basic medication of EH.

Adult↗
PubMed1998

[The reserve potentials of patients with ischemic heart disease who live under the conditions of an arid zone].

AIM: The study of physical performance of ischemic heart disease (IHD) patients in comfortable and uncomfortable (summer) weather conditions. MATERIALS AND METHODS: Systemic reserves were assessed by physical performance tests in comfortable weather (equivalent-effective temperature--EET 18-24 degrees C) and in heat discomfort (EET 25-30 degrees C), i.e. in summer when atmospheric oxygen is low (hyperthermic hypoxia). RESULTS: In uncomfortable weather, compared to comfortable one, general performance was significantly reduced evidencing uneffective function of the cardiovascular system. Comparison of the main ergometric parameters under the same load provides more accurate definition of the same trends in dynamics. CONCLUSION: General reserve in IHD patients is reduced under conditions of heart discomfort.

Adaptation, Physiological↗
PubMed1993

[Adaptive and non-adaptive reactions of central hemodynamics to conditions of heat discomfort].

Chest rheography was used to study central hemodynamics in 134 healthy males aged 18-28 in comfortable weather conditions and discomfortable ones, that is at equivalent-effective temperature 17-24 degrees C and above 27-30 degrees C, respectively. In trained subjects from native and non-native population under comfortable weather conditions heart rate (HR) proved to be significantly reduced as compared to untrained subjects (57.6 +/- 1.1 and 56.2 +/- 1.2 against 73.9 +/- 1.7 and 70.4 +/- 0.9), whereas stroke volume in trained males was significantly larger (by 14.2 and 14.0%, respectively). Minute blood volume (MBV), cardiac and stroke indices, systolic and diastolic pressure showed no significant differences. Heat discomfort gave rise to a slow-pulse trend in trained subjects from both native and non-native populations, in untrained subjects, especially non-natives heart rate accelerated. MBV increased in trained native and non-native examinees by 11.0 and 11.1%, respectively, while in untrained natives the rise reached 17.2%. This was secured by stroke volume elevation by 14.3, 10.7 and 11.2%, respectively (p < 0.05), in non-natives by acceleration of heart rate by 11.2%. A trend to lowering of arterial pressure was more marked in untrained examinees of both populations. It is evident that in conditions of arid zone heat discomfort trained subjects from both native and non-native populations exhibited adequate hemodynamic responses, whereas strain was observed in circulatory system functioning when it adapted to heat discomfort in untrained non-natives.

Acclimatization↗
PubMedDate not supplied

[Microcirculatory changes in patients with the initial manifestations of cerebral circulatory failure under the conditions of an arid zone].

Microcirculation was studied in 53 ICCD patients: 28 lived in comfortable weather conditions while 25 patients lived in heat discomfort in arid climatic zone. It is shown that heat discomfort led to compensatory microvascular reactions providing proper supply of oxygen to organs and tissues: tortuosity and dilation of the microvessels, opening of the capillaries, shunting in relative hypoxia and hyperthermia.

Adaptation, Physiological↗
PubMedDate not supplied

[Meteopathogenic mechanisms of exacerbating ischemic heart disease in an arid zone].

In arid zone of Uzbekistan summer heat discomfort aggravates the course of ischemic heart disease, provokes meteopathic reactions which we call "meteorological strain syndrome". In this season anginal attacks, episodes of arrhythmia and coronary failure become more frequent especially in patients over 70 years of age and migrants.

Adult↗
PubMedDate not supplied

[Adaptive and maladaptive reactions of the external respiration in the climatic conditions of an arid zone].

Physical performance was assessed in 134 healthy males aged 18-28, residents of the southern Uzbekistan. They were divided into two groups according to the results of bicycle exercise. Group I subjects (32 natives and 38 non-natives) exhibited high physical efficacy, group II subjects--low efficacy (30 and 34 natives and non-natives, respectively). Meteorotropic responses of the external respiration were studied in relation to thermal discomfort, sand storms eve and invasions. Group I subjects, natives in particular, responded by efficient and adequate external respiration, in contrast to group II non-natives who developed pulmonary hyperventilation. The latter is thought a compensatory reaction aimed at maintenance of homeostasis achieved at the expense of inefficient function of the respiratory system.

Adaptation, Physiological↗
PubMedDate not supplied

[The central hemodynamic reaction of patients with ischemic heart disease to the climatic and weather conditions of an arid zone].

Central hemodynamics of coronary patients living in the arid zone (215 males aged 40-72 and 150 females aged 40-75) was assessed in comfortable weather conditions, 1-2 days before the invasion of the dust storm, upon its invasion and in hot weather season (+26-30 degrees C). Angina of effort functional class I, II and III was in 102, 198 and 65 patients, respectively. Atmospheric conditions before the invasion of the dust storm form a hypoxic type of weather while on the day of the storm the weather appears spastic resulting in arterial hypertension, elevated total peripheral resistance and heart beat in diminution of cardiac output and stroke volume. Hot weather brings about a hypotensive response, total peripheral resistance falls, cardiac output increases at the expense of enhanced heart beat as stroke volume decreases. It is concluded that under the climatic conditions of an arid zone coronary patients develop a complex of hemodynamic responses which function with strain to supply blood to organs and tissues.

Adult↗
PubMedDate not supplied

[Effect of climate of arid zone on adaptive and non-adaptive changes in microcirculation].

State of microcirculatory bed of the bulbar conjunctiva and nail wall skin has been studied in 134 men (18-28 years old) of native (62 men) and non-native (72 men) population. It was found out that under heat discomfort the compensation is observed in native population due to the induration of the capillary network, opening of plasmatic capillaries which did not function before, tonus of venules and arterioles being preserved while the amount of "gigantic" capillaries increased. In this case the blood flow was entire, uniform and moderately accelerated. The number of functioning capillaries does not increase in non-native population, but arterioles does not increase in non-native population, but arterioles and venules were dilated, blood flow in them became more rapid, sludge-phenomenon of the I stage being observed in some people. Consequently, the observed changes in microcirculation under heat discomfort are insignificant in the native population due to available structure-morphological potentialities, while in non-native population these changes are accompanied by certain strain at the expense of available functional reserves.

Adaptation, Physiological↗