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Biomedical subjects

Z Plamieniak

Publications and source records attributed to Z Plamieniak.

At least 19 recordsLinked to original sources

Lipid disturbances in women with polycystic ovary syndrome.

Small but detectable disturbances concerning blood lipid levels manifested by somewhat higher concentrations of LDL-cholesterol and triglycerides as well as higher values of atherogenic indices expressing the ratio of cholesterol present in atherogenic lipoprotein fractions to that present in atheroprotective HDL fraction have been shown to exist in 36 women with polycystic ovary syndrome. HDL-cholesterol concentration was lower in women with polycystic ovary syndrome than in healthy women. The disturbances described above were more pronounced in obese patients. No correlation was found between the disturbances in lipid levels and hormonal disturbances particularly hyperandrogenemia.

Adult

[Atypical course of histiocytosis X].

A 48-year-old female patient was admitted because of increasing in size xanthomas of the eyelids lasting since 9 years (despite surgical treatment) and narrowing considerably the palpebral fissures. Five years earlier the diagnosis of type II b hyperlipoproteinaemia was made. Presently, besides palpebral lesions, a painless plum-sized tumour was found in the right frontoparietal area and two hard tumours of similar size were situated bilaterally in the submandibular area. In the biopsy specimens of all these tumours histological examination demonstrated lymphoid cells with numerous germinative centres. The diagnosis of histiocytosis X was followed by treatment with prednisone which resulted in a decrease in the size of palpebral xanthomas and improvement of the general condition of the patient.

Eyelid Diseases

Therapeutic effect of gevilon in patients with hyperlipoproteinaemia.

Authors examined 46 patients with hyperlipoproteinaemia divided according to hyperlipoproteinaemia type II A, II B, IV. After one month of isocaloric diet the patients were given a single night gevilon dose of 900 mg for a period of 3 months. After therapy we examined lipid metabolism, liver and kidney function, carbohydrate metabolism, hematopoietic system and water--electrolyte balance. In all groups increased levels of cholesterol, beta-lipoproteins and triglycerides were significantly reduced after 3 months of gevilon treatment. In all patients the HDL/LDL ratio increased close to normal values. No impairment of kidney or liver function hematopoietic system and electrolyte balance after 3 months of treatment were noted. Because gevilon is easy to apply and has a limited number of side effects, it is very readily taken by the patients who have lipid balance disorders.

Acetates