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Biomedical subjects

Z Mechl

Publications and source records attributed to Z Mechl.

70 records · Page 4Linked to original sources
PubMed1977

Some remarks to the histological classification of malignant melanoma of the skin and its prognostic values.

Histological classification of human skin malignant melanoma as recommended by WHO melanoma group renders the first useful orientation in regard to the biological behavior of the tumor, but it cannot give any further clinical outlook. It would be therefore desiderable to complete the histological examinations with enzymatic and immunologic examinations performed during the treatment of the patient and thus try to gain a basis for a prognostic evaluation.

Humans↗
PubMed1977

Cytologic diagnosis of malignant melanoma.

Cytology in malignant melanoma of the skin is a useful method, which alone yields in many cases enough diagnostic informations for a therapeutical approach. It is of a special importance in cases with marked anisocytosis of cells and with large, sometimes polynuclear cells and with cells with melanotic pigment. In cases with middle-sized apigmented cells of epitheloid appearance it should be always completed by biopsy, which, in these cases predominates over cytology. Combination of both methods brings a more substantial elucidation of diagnosis.

Cytodiagnosis↗
PubMed1976

On surgical treatment of malignant melanoma.

An early and adequate surgical intervention may have a favorable effect on the course of malignant melanoma (m.m.). Despite the focused publicity given to problems relating to m.m., faulty nonradical excisions of suspected pigmented lesions are still performed rather frequently in surgical outpatient departments. One of the reasons may be the rather difficult clinical diagnosis due to pleiomorphism of m.m., but a lack of experience of certain physicians is also responsible. The authors indicate what effective course to pursue in these patients. On the evidence of their set of 48 patients operated upon, they have shown a radical reexcision of the scar with its wide vicinity, following a nonradical intervention, to be justified. In certain cases, it may affect an eventful dissemination of tumorous cases, it may affect an eventual dissemination of tumorous cells in the close vicinity of the scar after an inadequate excision. In addition, they have delimitated indications valid for a radical reexcision.

Adult↗