[Ultrasonography, isotope scintigraphy and computerized tomography in the diagnosis of liver diseases].
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Biomedical subjects
Publications and source records attributed to Z Kalina.
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Serum concentrations of IgA, M, G and C-3 complement have been compared between 51 men occupationally exposed to chlorinated pesticides and 28 men of the control group. IgG has been found to be statistically significantly increased, whereas the concentration of IgM and C-3 complement--lower in the whole test group, as compared to the control group. These protein changes have been particularly strongly marked in the subgroup exposed to polycyclic chlorinated hydrocarbons. In the authors' opinion, the elevated IgG concentration in the occupationally exposed subgroup may result from immunostimulating effects of chlorinated pesticides, thus the decreased C-3 component of the complement in the serum in the test groups seems to be indicative of immune-complexes contribution to the pathogenesis of diseases resulting from the occupational exposure concerned. Furthermore, the authors suggest that the cyclic conformation of chlorinated pesticides may affect the pathomechanism of those diseases.
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In 36 workers occupationally exposed to polychlorinated pesticides (Gammexane, DDT) and in a control group, cytochemical investigations of lactate and succinate dehydrogenases (LDH and SDH, respectively) in peripheral blood leukocytes were performed. In comparison with the control group, in workers exposed to pesticides, reduction of colour intensity in neutrophiles for SDH and in lymphocytes both for SDH and LDH was observed. In discussion, an attempt was made to interpret the obtained investigation results which seem to indicate disturbances in pyruvate metabolism in peripheral blood lymphocytes.
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