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Biomedical subjects

Z Jiang

Publications and source records attributed to Z Jiang.

At least 325 records · Page 18Linked to original sources
PubMed1990

Effect of feeding cholesterol to laying hens and chicks on cholesterol metabolism in pre- and posthatch chicks.

Single Comb White Leghorn laying hens that were 60 wk of age were fed wheat and soybean meal diets containing either 0 or 1% cholesterol. Birds were artificially inseminated, and fertilized eggs were collected for incubation after a plateau of egg cholesterol content was reached. Posthatch chicks were raised with starter diets containing either 0 or .5% cholesterol. Samples of developing embryos and posthatch chicks at various stages were prepared for cholesterol analysis. As compared with controls, cholesterol content of eggs from hens fed 1.0% cholesterol diet was increased by approximately 70%. Embryos from the cholesterol-loaded eggs had significantly higher (P less than .05) cholesterol content. The plasma total cholesterol (TC) level in chicks from cholesterol-loaded eggs, when compared with TC in control eggs, was significantly higher at hatching but decreased to the same level by 2 wk after hatching. Cholesterol feeding to newly hatched chicks elevated plasma TC and high-density lipoprotein cholesterol levels. The TC contents of liver and heart, but not skeletal muscle, were significantly higher in chicks fed the .5% cholesterol starter diet than those fed the cholesterol-free diet. These results show that cholesterol metabolism in developing embryos and posthatch chicks is influenced by cholesterol in both maternal and chick diets.

Animals↗
PubMed1990

[Pathological analysis of lymphonoidi coeliac in patients with schistosomiasis].

In specimens from 75 cases of abdominal operation, it was found that ova of schistosoma had deposited in 108 lymphonodi, including 62 lymphoglandulae coelacae and 46 lymphoflandulae mesentericae. Quantity of eggs in lymphonodi and 4 conditions of reactions, i.e. sparse distribution, massive lumping, chronic egg-knotting and mixed presence, were studied and analyzed pathologically. The possible ways in which the ova reversely penetrate the lymph nodes through the vein are analyzed and discussed.

Adult↗
PubMed1990

[Drug abuse among residents of Beijing: an epidemiologic survey of 1,822 households].

An epidemiological survey was conducted in the residential areas of 6 neighbourhood committees of Chao Yang District of Beijing in search of the prevalent status and related factors of drug abuse among 1,822 households out of 6,114 population. The result of present study reveals that the prevalence rate of limit daily-used drug abuse is 3.09% among a sample of 5,509 people over the age of fifteen. However, the extent of drug abuse seems neither great nor epidemic and all 17 dependents living in scattered geographical sites. In exploring the causation of drug abuse, the authors found that family structure, economic status, individual social function or stressful life events are not correlated and the use of drug is not a coping method to environmental maladaptation. On the contrary, most of the drug dependent are attributable to some iatrogenic reasons lacking of certain drug monitoring measures in their long-term medication. In a word, the misuse of drug facilitated addictive behaviors. No social problem emerged among all cases of study as measured with SDSS, but it is still a potential hazard to the psychosomatic health condition in the long run.

Adult↗
PubMed1990

[Purification and identification of antimicrobial peptides of rabbit neutrophils].

Five antimicrobial peptides were extracted from the cytoplasmic granules of rabbit neutrophils with 0.01 mol/L citric acid. SDS-PAGE gel densitometric analysis of the citric acid extract showed that they accounted for 34%-42% of the total extract proteins. When subjected to acid urea polyacrylamide gel electrophoresis, five peptides migrated much further to the cathode than lysozyme. Beginning with the most cathodal component, they were in turn referred to as NP1, NP2, NP3, NP4, and NP5. They were purified from the citric acid extract by virtue of preparative polyacrylamide gel electrophoresis. Each of them was of low molecular weight (2,500-6,000) as determined by SDS-PAGE. Three of the peptides were tested in vitro for fungicidal activity. When Candida albicans (10(7)/ml) were incubated with 12.5 micrograms/ml of NP1 or NP2 at 37 degrees C for 2 h, the death rates of the organisms were 96.6% and 93.3% respectively. NP3 was shown to be active against Candida albicans although less potent than NP1 and NP2.

Animals↗
PubMed1990

Immunopathology of diabetes in the RT6-depleted diabetes-resistant BB/Wor rat.

Insulin-dependent diabetes mellitus appears to be an autoimmune disease that is characterized morphologically by insulitis, an inflammation of the pancreatic islets of Langerhans that results in the destruction of the insulin-producing beta cells. The RT6-depleted DR rat provides a good model for the in situ study of insulitis. The authors used the anti-RT6.1 monoclonal antibody to selectively deplete RT6 T cells in DR rats and produce a synchronous and rapid development of insulitis that commences 10 days after treatment. The phenotype of cells that infiltrated the islets at different stages of insulitis in the RT6-depleted DR rat was determined by immunocytochemical techniques. A prodromal period of 10 days was present in which the authors could not detect morphologic alterations within the pancreas. This is followed by a second phase of early insulitis in which a few islets are infiltrated by macrophages and T cells. This rapidly progresses by 18 days to the final phase of generalized insulitis in which the islets are massively infiltrated by macrophages and T cells.

Animals↗
PubMed1989

Studies of beta-thalassemia mutations in families living in three provinces in southern China.

beta-Thalassemia is a common disease in Southern China and 10 different mutations or frameshifts are responsible for most types of beta-thalassemia in this area. We studied 126 chromosomes of 80 beta-thalassemia patients from the Guangxi, Guangdong, and Sichuan Provinces using the polymerase chain reaction followed by dot-blot hybridization with specific oligonucleotide probes. The most common mutation in the three provinces is the frameshift at codons 41-42, followed by the A----T mutation at codon 17. The A----G mutation at nt -29 of the promoter is common in Sichuan but not in the other two provinces. Three mutations (T----C at nt -30; G----T at IVS-I-1, and G----C at IVS-I-5) were not observed. These data were used to initiate a prenatal diagnosis program using the same techniques for identification. Eleven fetuses at risk for beta-thalassemia have been diagnosed.

Base Sequence↗
PubMed1989

[Primary intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses].

Forty-nine cases of adenocarcinoma of the nasal cavity and paranasal sinuses were reviewed, in which 5 cases showed a marked similarity to colonic adenocarcinoma. Diagnosis of intestinal-type adenocarcinoma chiefly depends on pathological examination and mucous staining. Although well differentiated, the intestinal-type adenocarcinoma has a marked propensity for recurrence and a lethal potential.

Adenocarcinoma↗