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Biomedical subjects

Z G Makura

Publications and source records attributed to Z G Makura.

11 recordsLinked to original sources

Globus pharyngeus: a postal questionnaire survey of UK ENT consultants.

Globus pharyngeus is a common complaint often referred to the ENT outpatient department. The precise nature of globus pharyngeus and its aetiology remains something of a mystery. There is no uniform policy of management of this condition. A postal questionnaire was sent to all UK-based ENT consultants registered with the British Association of Otorhinolaryngolgists-Head and Neck Surgeons (BAO-HNS). The aim of this study was to ascertain if there was a favoured management policy by the majority of consultants. Our results indicate that there is a lack of consensus in the investigation and management of globus pharyngeus. Fourteen per cent do not perform any investigations, but would prescribe antacid medication if clinically indicated. The remainder would investigate in a variety of ways. The most common investigation is rigid endoscopy which is performed by 61% of respondents, followed by barium swallow (56%). The combination of endoscopy and barium swallow is routinely performed by 17.5% of respondents.

Barium Radioisotopes↗

Glossopharyngeal neuralgia following foreign body impaction in the neck.

Glossopharyngeal neuralgia is rare, typically idiopathic and treated with carbamazepine. Surgery to decompress or transect the glossopharyngeal nerve root may be performed if conservative management fails. We present a case following trauma to the neck with foreign body impaction. To our knowledge this is the first case of glossopharyngeal neuralgia due to neck trauma.

Adult↗

Topical aminoglycosides in the management of active mucosal chronic suppurative otitis media.

Debate has currently re-emerged following a renewed warning issued from the Committee on the Safety of Medicines (CSM) regarding the relative risk of ototoxicity from the use of aminoglycoside-containing drops in patients with tympanic membrane perforations. We present the findings of a survey of ENT consultants, questioning their views and current practice, and we add to the debate by means of a review and discussion of the literature.

Administration, Topical↗

Paediatric tympanoplasty.

Much debate exists over the management of mucosal chronic suppurative otitis media in children, with the majority of it centred around the correct timing to perform either a myringoplasty (an operative repair of the tympanic membrane) or type I tympanoplasty (reconstruction of the tympanic membrane when there is an intact and mobile ossicular chain). Further discussion will use the term tympanoplasty to mean both of the above definitions. We present the findings of a recent survey of UK ENT consultants questioning their opinions on various management aspects of mucosal CSOM in the paediatric population. We also present an extensive review of the literature to provide us with published evidence in order to analyse the results of the questionnaire.

Adolescent↗

Wegener's granulomatosis presenting as a temporal headache.

Formerly a fatal condition, Wegener's granulomatosis is now treated with good results. Clinical morbidity is often due to failure by clinicians to make the diagnosis. Many patients (including our cases reported here) present with atypical symptoms, and only a high index of suspicion will ensure early diagnosis. Classical chest and renal symptoms often indicate late stage disease. We present two cases that underline the limitations of current 'diagnostic' immunological tests whilst emphasising the importance of clinical features in diagnosis. Standard treatment with Cytotoxic agents and corticosteroids are effective but carry considerable morbidity. We have followed the current trend of incorporating a less toxic antibiotic agent in the management of this enigmatic condition.

Adult↗

The clunking neck.

A patient complaining of pain and noise on turning her neck was diagnosed as having a large greater cornua of the hyoid bone. Excision of the greater cornua relieved the symptoms.

Adult↗

Cancer of the larynx at Harare Central Hospital in Zimbabwe.

This study presents a review of 114 patients with carcinoma of the larynx who presented at Harare Central Hospital (HCH) between January 1985 and December 1991. Ninety seven of the patients were mainly in the 50-75 age group. Most of the patients presented late and there were no cases of carcinoma in situ noted. Twenty pc had receiving treatment as asthmatics or they came with a referral diagnosis of asthma which contributed to delay in proper treatment. Sixty two pc were glottic, 26pc supraglottic and two pc were subglottic. It was not possible to state the primary site in 10pc. All were squamous cell carcinomas.

Adult↗

The second tour.

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Internship and Residency↗

Competent inadequacy.

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Attitude of Health Personnel↗