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Biomedical subjects

Z Fumeaux

Publications and source records attributed to Z Fumeaux.

2 recordsLinked to original sources

[Urine electrolytes: use and pitfalls to avoid].

In clinical situations of electrolytic or acid-base disorders, the measure of electrolytes concentration and osmolality in a urine sample, which is called the urinary spot, is a simple way to guide the diagnosis and therapy. The interpretation of results must take into account the patient's history and clinical examination. The urine sodium concentration and urine osmolality are key elements in the diagnosis of dysnatremias and in renal failure. The urine chloride concentration is useful in the diagnosis of acid-base disorders. The potassium excretion in the urine, which is regulated mainly by aldosterone, is particularly helpful in the case of hypokaliemia. Finally, the determination of the transtubular potassium gradient is a valuable tool for the diagnosis of hypoaldosteronism.

Acid-Base Equilibrium↗

[Nephrology].

Alternative to nephrotoxic calcineurin inhibitors regimens are feasible in renal transplantation. Sirolimus is an effective immunosuppressive drug with less drug-induced nephrotoxicity. Enteric-coated mycophenolate sodium provides a safety and efficacy alternative to mycophenolate mofetil. In peritoneal effluent, cancer antigen 125 (Ca 125) is a mesothelial cell marker and of in vivo biocompatibility of the new dialysis solutions. Longterm PD and peritoneal sclerosis are associated with a low number of mesothelial cells and a low concentration of dialysate Ca 125. Exposure to glucose and degradation products (GDPs) is important in the genesis of mesothelial damage. Short results of the more biocompatible solutions are promising (increasing of Ca 125). In the future, exposure to glucose can be reduced by using combinations of various osmotic agents, each in a low concentration (glycerol and amino acid solution).

Humans↗