[Primary prevention of ischemic heart disease using clofibrate. Cooperative epidemiological study].
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Biomedical subjects
Publications and source records attributed to Z Fejfar.
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The fall in the ventricular fibrillation threshold during the first half an hour following ligation of the descending branch of the left coronary artery in dog was not influenced by the i.v. injection of trimecain (Mesokain Spofa). On the other hand, an i.v. injection of methypranol (Trimepranol Spofa) given prior to ligation increased the level of ventricular fibrillation threshold 3 to 4 times compared to control value before occlusion in all 10 studied dogs. Depression of the beta-blocking adrenergic activity may thus prevent the occurrence of ventricular fibrillation in acute myocardial ischaemia.
This paper describes the current state of surveillance and monitoring of acute, chronic and asymptomatic cardiovascular disease with particular reference to the situation in Czechoslovakia. It goes on to discuss some of the difficulties involved in obtaining adequate data on which to base surveillance and of creating a coherent central information system. The importance of combining registration or notification with active intervention is emphasized, and the possible suggested of introducing simple techniques of cardiovascular investigation into health screening procedures or consultations established primarily for another purpose.
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One hundred office workers measured their own blood pressure at their place of work twice a day for 3 weeks. No technical difficulties or adverse psychological reactions were observed. Of 85 answers to a questionnaire, 64 indicated a preference for self-measurement to measurements made by a physician or nurse. Variations of blood pressure showed no relationship to the actual pressure. A preference for the digits 0 and 5 was observed.
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