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Biomedical subjects

Z E Deeb

Publications and source records attributed to Z E Deeb.

27 records · Page 2Linked to original sources

Actinomycotic osteomyelitis of the facial bones and mandible.

Actinomyces israelii is a part of the human oral flora and thus is more commensal than pathogenic. Oral trauma, accidental or purposeful, can precipitate its introduction into the soft tissues, to which infection is usually confined. The case presented is one in which, over a span of two decades (1956 to 1977), the extraction of a mandibular tooth resulted in a chronic actinomycotic osteomyelitis, destroying first the mandible, then both maxillae, and then the right zygoma, with decreased vision and proptosis despite repeated medical and surgical intervention. Adequate treatment required removal of the sequestrum and excision of all infected granulation tissue, scars, and involucra until healthy bone was exposed. Intravenous penicillin was administered for 2 weeks, followed by a 6-month course of oral penicillin. The patient was followed for 4 years and remained disease free.

Actinomycosis↗

The association of chronic inflammatory disease in lichen planus with cancer of the oral cavity.

Heavy cigarette smoking and alcohol consumption are the major contributing factors in the development of cancer of the upper aerodigestive tract. Other factors, such as chewing substances and chronic irritation, have been implicated. The purpose of this presentation is to draw attention to chronic inflammation as another likely etiologic factor in the pathogenesis of oral cavity cancer. During the past 4 years, we diagnosed squamous cell carcinoma of the oral cavity in six consecutive patients who had no history of cigarette smoking, alcohol intake, or substance abuse. Although this series is too small for significant analysis, it does suggest that chronic inflammatory processes such as lichen planus and chronic gingivitis can induce neoplastic metaplasia in the epithelium of the oral cavity.

Aged↗

Plain roentgenography in the evaluation of unilateral vocal cord mobility.

Despite the availability of many methods for the structural and functional evaluation of the larynx, this study suggests that plain roentgenographic techniques are simple and effective means of providing diagnostic and prognostic data useful in the management of hemilaryngeal dysfunction. Lateral soft tissue and anteroposterior views of the neck can demonstrate unilateral vocal cord dysfunction within a few hours after onset. Complete recovery of vocal cord function is most likely to occur when hemilaryngeal dysfunction is not associated with the appearance of a distended ventricle on the lateral soft tissue roentgenogram of the neck. Conversely, when the distended ventricle assumes a delta or Y configuration, it is unlikely that the hemilarynx will resume its normal mobility. Laryngeal immobility lasting more than six months is usually irreversible.

Adult↗

Acute supraglottitis in adults: early indicators of airway obstruction.

PURPOSE: To show that cardinal signs of upper airway obstruction are characteristically absent in the early phases of potentially fatal supraglottitis. PATIENTS AND METHODS: The hospital records of 9 previously healthy adults who died from autopsy-proven supraglottitis within 12 hours after sudden onset of severe sore throat. RESULTS: Six patients who were discharged from the emergency room with a diagnosis of pharyngitis died at home within 4 hours after dismissal. Three patients suspected of supraglottitis were admitted and treated medically; by the time signs of respiratory obstruction appeared, attempts at airway intervention failed. None of the 9 patients presented with symptoms or signs of respiratory distress, but all gave a history of fulminant sore throat associated with chills and fever. In all patients, the pulse rate was above 100 per minute. CONCLUSION: In the early phases of acute supraglottitis, the most reliable indicator of impending airway obstruction is a rapidly developing severe sore throat. Dyspnea, tachypnea, retractions, stridor, and cyanosis are manifestations of advanced stages of the infection and should not be awaited to determine the need for airway intervention.

Adult↗

Parathyroid tumors as lateral pharyngeal masses: report of a case.

This is the first reported case in the literature describing a patient free of the systemic biochemical effects of hyperparathyroidism who presented with a lateral pharyngeal mass. Diagnosis of parathyroid adenoma was made by means of a transoral biopsy prior to definitive surgical treatment. The role of parathyroid lesions in lateral cervical masses is discussed.

Adenoma↗