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Biomedical subjects

Z Bárdosi

Publications and source records attributed to Z Bárdosi.

18 recordsLinked to original sources
PubMed1998

[Mass spectrometry in the verification of pyrimethamine poisoning].

A 17 years old male patient with Pyrimethamin therapy was released from our department by emphasising the necessity of continuous control. A month later the patient was accepted again with serious anaemia. Since the patient did not follow the instructions Pyrimethamin intoxication was presumed, but it had to be proved. At last the drug in the plasma was identified and quantified by mass spectrometry. The plasma concentration of Pyrimethamin was five times higher than the therapeutic level. The rapid analysis (4 hours after taking of blood) and adequate treatment resulted in rapid improvement with the concomitant decrease of plasma Pyrimethamin concentration. During clinical treatment the level of Pyrimethamin in the plasma was followed by mass spectrometry.

Adolescent↗
PubMed1994

Myasthenia gravis: effect of immunoactive therapies.

New immunoactive therapies, plasmapheresis, intravenous steroid pulse infusion and intravenous immunoglobulins were examined for efficacy on the basis of large casuistics of myasthenia gravis. The best results were achieved with combination of these procedures. Indications of the new methods: (i) respiratory crisis of any character (myasthenic, cholinergic or mixed oscillating crisis); (ii) the patients' preparation for thymectomy; (iii) post-thymectomy therapy aimed at improving the patients condition, at avoiding relapses, at shortening the time of steroid therapy and at repressing cholinergic drug therapy; (iv) patients of old age in crisis-prone state. The new methods, together with thymectomy, steroid therapy and immunosuppression, represent a very efficient and promising new way toward modern therapy of myasthenia gravis.

Adolescent↗
PubMed1980

[Therapy of adult respiratory distress syndrome].

After a brief review of the pertaining literature, 10 patients treated for adult respiratory distress syndrome between 1974 and 1978 are reported. Eight patients died; in 4 cases the cause of death was some other irreversible lesion. Respirator treatment with the Bird-8 apparatus was supplemented with cardiac diuretic and antibiotic therapy. Improvement of the results can be hoped partly from prevention, partly from the early diagnosis of ARDS and its adequate treatment.

Adult↗