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Biomedical subjects

Z A Avetisian

Publications and source records attributed to Z A Avetisian.

4 recordsLinked to original sources
PubMed2004

[Protective effect of Vipera raddei venom damage of peripheral nerve].

In rats, single pulse activity of inter- and motoneurons of the spinal cord lumbar segment was studied in stimulation of cut. n. ischiadicus, extensor (n. gastrocnemius) and flexor (n. peroneus communis) after treatment with the Viper raddei venom for 4 weeks. In the control rats, no responses occurred in the n. ischiadicus distal stump, whereas the responses to contralateral nerve stimulation did occur. On the intact side, the responses occurred in opposite sequence. The absence of effects of the cut nerve distal stump stimulation in control rats resulted from the coalescence absence in the proximal stump which suggests atrophy of the distal stump. Morphological data prove a distal stump hypertrophy and restoration of the affected limb motor activity. The findings suggest a possibility of application of the Viper raddei venom for regeneration of injured peripheral nerve.

Animals↗
PubMed1991

[Plastic changes in the intact cerebral cortex resulting from local damage to its symmetrical section].

Representation of the radial nerve in symmetrical area of the opposite hemisphere was studied in cats using the recording of focal potentials within 1.5-1.8 months after electrolytic destruction of the associative parietal cortex. Increasing of the radial nerve representation area occurred within 3-4 months after the operation. The activity of lactatdehydrogenase and malatdehydrogenase, as well as the spectrum of the lactatdehydrogenase isoenzymes, were studied during the same period.

Animals↗
PubMed1985

[Electrophysiological study of the role of the cerebral cortex in the compensatory recovery of functions].

Intracortical rearrangement of functions in the process of the compensatory rehabilitation of functions was studied in semichronical experiments using the technique of recording focal potentials in the parietal associative and somatosensory cortex after unilateral extirpation of their symmetrical regions. The recording zones for the focal associative and somatosensory (projecting) potentials were found to extend following the complete intracortical rearrangement (8-10 months after the unilateral extirpation). An assumption based on changes in the time-amplitude characteristics of the parameters of focal potentials recorded on the surface and at various levels of the somatosensory cortex of the intact hemisphere, was made that the positive wave of the focal surface response is not the result of deep (inner) negative potentials. As to the associative focal responses--no reversion of them could be observed across the whole depth of the cortex.

Adaptation, Physiological↗