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Biomedical subjects

Yue-qin Huang

Publications and source records attributed to Yue-qin Huang.

3 recordsLinked to original sources

[A twin study of personality disorder heritability].

OBJECTIVE: To calculate heritabilities of personality disorders (PDs) in twin population. METHODS: Based on informed consent, we used Personality Diagnostic Questionnaire (fourth-version) as our screening tool to study the adult twins (aged 20 - 70 years) in Qingdao city. There were 324 twin pairs whose zygosity had been determined. Structural equation modeling was used to estimate the heritabilities by 242 same-sex twin pairs. RESULTS: The best-fitting models yielded a heritability of 68.26% (60.26 - 74.78) of overall PDs, 59.00% (49.22 - 67.17) of cluster A, 64.99% (56.24 - 72.16) of cluster B, and 63.66% (54.72 - 71.02) of cluster C. There were significant genetic effects for schizotypal, narcissistic and dependent, explaining 49.96% (37.94 - 60.14), 52.89% (41.85 - 62.24) and 68.87% (60.80 - 75.40) of the variance respectively. No genetic effects were found on Histrionic, but common environmental effect accounted for 54.08% (44.50 - 62.43) of the total variances. CONCLUSION: PD was mainly determined by genetic factor. These findings may provide evidence for future research on PD.

Adult↗

[Study on the psychosocial status and related factors in three universities during severe acute respiratory syndrome epidemic in Beijing].

OBJECTIVE: To investigate the psychosocial status and related factors among university students during severe acute respiratory syndrome (SARS) epidemic in Beijing. METHODS: By means of stratified cluster sampling, symptom checklist-90 (SCL-90) and questionnaire on general information were applied among 6800 students in three universities in Beijing. RESULTS: There were 6280 valid questionnaires gathered. In order to control and prevent SARS, strict management was conducted in three universities which providing various social supports. Out of the 6280 students, 460 had SCL-90 positive symptoms with a rate of 7.3%. Risk factors of SCL-90 positive symptom were found as follows: major in arts (OR = 2.00), misconception on the control and prevention of SARS (OR = 1.91), considering measures non-effective (OR = 2.25), and do not believe that SARS can be under control (OR = 3.57). Protective factors of SCL-90 positive symptom would include as: being female (OR = 0.77), being graduate students (OR = 0.38), and being not much influenced on study and daily life during the period of strict management (OR = 0.54). CONCLUSION: Psychosocial status of students was influenced by their knowledge and attitude on SARS. Various social supports might keep the university students to having a healthy psychosocial status.

Adolescent↗

[A nested case-control study on child sensory integrative dysfunction].

OBJECTIVE: To explore risk factors and protective factors of sensory integrative dysfunction (SID) among preschool and school children in Beijing, and to identify potential risk factors of SID. METHODS: Three hundred and ten kindergarten children were investigated twice in 1993 and 1999 by "The Child Sensory Integration Check List" and "General Information Questionnaire". A nested case-control study was carried out by single variable and multivariate conditional logistic regression analysis to find out the risk factors of SID. RESULTS: In the SID incidence group, the risk factors of SID were edema during pregnancy (OR = 7.06), paternal age (OR = 1.28), suffering from diseases before 3 years old (OR = 1.13), while the protective factor was family support network during school age (OR = 0.54). In the SID self-recovery group, the risk factors of SID were suspected attention-deficit hyperactivity disorder (ADHD) among maternal cousins (OR = 3.02), social ethos (OR = 1.69), consistency of parental discipline (OR = 1.45), while the protective factors were living condition and environment for entertainment (OR = 0.37), parental care during school age. In the SID negative group, the risk factors of SID were maternal contracted pelvis (OR = 3.45), less chance in enjoying audio and video entertainment during school age (OR = 1.98), suspected ADHD among paternal cousins (OR = 1.89), consistency of parental discipline (OR = 1.75), suspected ADHD among maternal cousins (OR = 1.48), paternal occupation during school age (OR = 1.19), while the protective factors were family support network (OR = 0.56) and maternal educational background (OR = 0.38) during preschool age. CONCLUSION: Our data showed that the risk factors of child SID were mainly associated with biological and genetic factors. Psychosocial factors seemed to be the secondary risk factors of SID.

Attention Deficit Disorder with Hyperactivity↗