Yi-Ching Lynn Ho | Search PubMed

PubMed2005

Functional magnetic resonance imaging in adult craniopagus for presurgical evaluation.

Cranially conjoined twins are rare and pose unique challenges in the preoperative evaluation of cerebral language function. The authors report on their experience in the functional magnetic resonance (fMR) imaging evaluation of adult craniopagus (temporoparietooccipital fusion) to evaluate hemispheric language dominance and the eloquent language areas in the preoperative planning stages. Conventional clinical imaging hardware originally designed for individuals was adapted and tailored for use in the twins. They were assigned a selection of language tasks while undergoing fMR imaging. Significant blood oxygen level-dependent activations were detected in the main language regions in each twin, that is, the inferior frontal gyrus (around the Broca area), the middle and superior temporal lobes (around the Wernicke area) together with the inferior parietal lobe, and the middle and superior frontal gyri. Overall, the right-handed twin was strongly left lateralized for language, whereas the left-handed twin showed more bilateral activation during language tasks. Noninvasive language mapping with the aid of fMR imaging has been demonstrated for the first time in total craniopagus.

Adult↗

PubMed2004

Parallel imaging techniques in functional MRI.

Originally developed for increased scanning velocity in cardiac imaging, parallel imaging (PI) techniques have recently also been applied for the reduction of artifacts in single-shot techniques. In functional brain imaging (fMRI) techniques, PI has been used for several purposes. It has been applied to reduce the distortions caused by the length of the echo-planar imaging readout, diminution of the gradient-related acoustic noise, as a means to increase acquisition speed or to increase the achievable brain coverage per unit time. In this article, the different applications of PI techniques in fMRI are reviewed, together with the basic theoretical background and the recently developed hardware necessary to achieve rapid, high signal-to-noise ratio PI-fMRI.

Artifacts↗