Biomedical subjects

Ye Lin

Publications and source records attributed to Ye Lin.

At least 19 recordsLinked to original sources

PubMed2006

Adolescent lumbar disc herniation and hamstring tightness: review of 16 cases.

STUDY DESIGN: Retrospective review. OBJECTIVES: To investigate the clinical characteristics and responses to surgical and conservative treatments of lumbar disc herniation in adolescents with hamstring tightness. SUMMARY OF BACKGROUND DATA: The incidence of hamstring tightness in adolescent lumbar disc herniation is much higher than that of adults. Hamstring tightness has been reported to result from nerve root or cauda equina irritation. But the clinical characteristics, prognosis, and etiologic mechanism of hamstring tightness has not been clearly investigated. METHODS: Sixteen consecutive adolescents (age range, 12-18 years; mean, 15.8 years) with lumbar disc herniation were analyzed. Among them, there were 10 cases with hamstring tightness. Clinical and radiologic findings of the study group were compared with those of the remaining 6 cases. After conservative treatment, 5 cases in the hamstring tightness group were treated with discectomy, and of these, 1 case was treated with shortening osteotomy in the upper part of the bilateral femurs 10 months after the discectomy because of the persisting hamstring tightness. Another 5 discectomies were done in the nonhamstring tightness group. All patients were observed for a mean of 2.7 years (range, 0.8-6 years). RESULTS: In all patients, the neurologic defects were improved shortly after the treatment, but the hamstring tightness continued and remained even after 1 year. The patient who underwent femoral osteotomy showed improvement. CONCLUSIONS: The incidence of hamstring tightness in adolescent lumbar disc herniation is high. The physical examination findings and prognoses of patients with hamstring tightness are different from those of simple disc herniation patients. The hamstring tightness appeared to have developed from a different mechanism.

Adolescent↗

PubMed2006

Dynamic canal encroachment of ligamentum flavum: an in vitro study of cadaveric specimens.

OBJECTIVE: In extension of the cervical spine, the ligamentum flavum (LF) may bulge and intrude into the vertebral canal and cause symptoms of myelopathy and/or radiculopathy in patients with canal stenosis. Knowledge of the relationship between the extension angle and the physiologic changes of the LF is important for a better understanding of the clinical symptoms. The current study was designed to demonstrate the dynamic correlativity of canal intrusion of the LF bulge with the extension angle of the cervical spine. METHODS: With a novel method, the probe of the electrical resistance strain gauge was put into the cervical canals of 14 cadaveric specimens. The LF bulge distance of six segments (C2-C3 to C7-T1) and corresponding extension angles of every 5 degrees from 0 degrees to 45 degrees were collected. Angle-bulge curves were drawn. RESULTS: In overextension (45 degrees ), C5-C6 had the biggest canal intrusion depth (3.478+/-0.527 mm), whereas the upper and lower segments declined gradually (C5-C6>C4-C5>C6-C7>C3-C4>C7-T1>C2-C3). The curves in all segments were sigmoidal, which demonstrated the dynamic change of LF, that is, during the process of extension, LF shortened and contracted first, after the original length was reached, it began to bulge and burst into the canal. CONCLUSION: The current study has provided a method to measure inner canal kinematic changes in intact spinal specimens.

Adult↗

PubMed2006

[Clinical study of implant-retained facial prosthesis].

OBJECTIVE: To evaluate clinical results and technical characteristics of implant-retained facial prosthesis. METHODS: Six patients with facial defects underwent implant retained prosthesis treatment, of which 3 orbita defects (including upper and lower eyelids, eyeball) in 3 cases, 2 ears defects in 2 cases, and a nose defect in one case. Under local anaesthesia 21 extra-oral implant were placed, facial prosthesis were individually made six month postoperatively. Follow up ranged from 6 month to 6 years. RESULTS: All 21 implants osseointegrated well, implant lost and peri implantitis was not found. All 6 cases had individual facial prosthesis and were satisfied with the prosthesis. CONCLUSIONS: Extra oral implants provided excellent retainment for facial prosthesis; result of current silicon with individual color shade is encouragable.

Dental Prosthesis, Implant-Supported↗

PubMed2006

[A clinical retrospective study of 10 years implant results].

OBJECTIVE: To evaluate ten years clinical results of dental implant treatment. METHODS: A total of 5,590 endosseous implants were consecutively placed from Aug. 1994 to Aug 2004 in Center of Implantation, Peking University School and Hospital of Stomatology. Among them, 161 were Brånemark implants, 1,436 were Frialit-2 implants, 1,012 were IMZ implants, 767 were Ankylos implants, 2,189 were Camlog implants, and 25 were Komet implants. A total of 2,629 prostheses were delivered, including 2,314 fixed prostheses and 315 implant-supported removable dentures. The patient age range was between 17 and 82. The mean follow-up time was 77.2 months (7 to 121 months). Clinical examination and X-ray films were conducted. The results were evaluated with Wheeler's survival criteria. RESULTS: With the final prostheses, 2,624 patients were satisfied. Five patients were unsatisfied with the prostheses. With refabricating the prostheses, 4 patients were satisfied and one expressed as acceptable. Peri-implantitis was observed in 178 implants of 105 cases. Prostheses loose was observed in 21 cases and fracture in 4 cases. Ceramic crack was observed in 51 cases. The documented implants lost were 68. The implant survival rate was 96.7% according to Wheeler's survival criteria. CONCLUSIONS: Implant prostheses were with high satisfaction. The implant survival rate was as highly as 96.7%. Implant prostheses were indicated for almost all the partial and complete edentulous cases due to modern implant surgical technique.

Dental Implantation, Endosseous↗

PubMed2006

[Evaluation of clinical results on osteotome sinus floor elevation and dental implant placement (122 cases report)].

OBJECTIVE: To evaluate the clinical results of osteotome sinus floor elevation technique in the posterior maxillary region. METHODS: A total of 122 patients underwent osteotome sinus floor elevation from July 1998 to July 2004. Forty-eight cases were male and 74 were female. The mean age was 46.5 years (between 20 and 69). A total of 157 implants were placed and restored. The mean follow-up time was 29.7 months (between 14 and 84 months). Clinical examination and radiographs were conducted. All the patients with 8 - 11 mm height of residual bone in the posterior maxilla underwent sinus floor elevation and implant placement using osteotome without any bone grafts simultaneously. The elevation height was 2 - 5 mm. Healing abutments were connected at the same time of implant placement with insertion torque over 0.25 N.m and the final prostheses were restored after 3 - 4 months. Implants were submerged if the insertion torque was less than 0.25 N.m. Second-stage operation was conducted 3 - 4 months later and the implants were restored afterwards. RESULTS: Sinus membrane perforation was observed in 12 cases, no sinus complication was observed during the follow-up. All of the 157 implants gained osteointegration and were restored. No implant lost was observed during the follow-up. All the patients were satisfied with the final prostheses. CONCLUSIONS: Osteotome sinus floor elevation without any bone graft was a predictable and safe technique. It could be used in the maxillary posterior area implant placement with residual bone volume of 8 - 11 mm.

Adult↗

PubMed2006

[Clinical application of implant supported magnet-retained overdenture].

OBJECTIVE: To evaluate the clinical effects of implants supported magnet-retained overdenture. METHODS: From November 1999 to March 2005, 25 cases with edentulous jaws underwent implant-supported magnet-retained overdenture. Among them, 14 patients were male, 11 patients were female. The average age of the patients was 67.6 years. (Range 45 - 79 years). Ninety-five implants used included Komet (18), IMZ (11), Frialit-2 (12), Ankylos (10), Camlog (44). The fellow-up time was from 6 months to 70 months. Clinical examination and radiographs were conducted. RESULTS: No infections, nerve or sinus damage or other sequelae occurred. The overdentures were stable and functioned effectively. From November 1999 to March 2005, One Komet abutment was fracture and 1 Frialit-2 implant was lost because of overloading during follow-up. The remaining implants achieved successful osseointegration. Patients were satisfied with the treatment. CONCLUSIONS: Implant-supported magnet-retained overdenture was a predictable and reliable method, especially for old patients with edentulous jaws.

Aged↗

PubMed2006

[Preliminary clinical study of microimplants in the restoration of edentulous jaws].

OBJECTIVE: To investigate if magnetic- attached overdenture supported by microimplants of 2.5 mm in diameter was able to function properly. METHODS: Fourteen microimplants were placed in 4 patients. Implants were exposed 3 months later and magnetic abutments were connected directly. X-ray was taken during the 3 year follow-up to examine marginal bone level. Peri-implant soft tissue was also checked. Denture retention, chewing stability and overall satisfaction with the microimplants retained overdenture were evaluated. RESULTS: All of the 14 microimplants achieved initial primary stability without infection or any other postoperative complications. No implant was lost during the follow-up period. Only one magnetic abutment fractured one year after restoration and was replaced. X-ray showed highly stable marginal bone level around the microimplants. The patients were satisfied with the restoration. CONCLUSIONS: The microimplants retained overdenture leads to a significant improvement of function despite of the small dimensions of these implants. In particular for elder patients with severe residual ridge resorption, this treatment represents a less invasive alternative compared to conventional implant systems.

Aged↗

PubMed2006

[Clinical study of periocline on peri-implantitis treatment].

OBJECTIVE: To evaluate the clinical outcome and the effects of treating peri-implantitis with periocline. METHODS: Thirty-two sites in 32 implants with peri-implantitis were treated with periocline. The parameters including plaque index, probing depth (PD) of pocket, sulcular bleeding index (SBI) were measured at baseline, 1, 3, 6 and 12 weeks after treatment and followed up for 6 months. RESULTS: Statistically significant decrease (P < 0.05) in SBI, and PD occurred at all time intervals compared to baseline. The treatment could last for at lest four weeks in peri-implantitis cases without fistula. CONCLUSIONS: Periocline could be safely and effectively used in treating peri-implantitis in cases without peri-implant fistula. Peri-implantitis with fistula should be treated in combination with surgical methods, and periocline can also be used to control inflammation before surgery.

Adult↗

PubMed2006

[Effects of the HLA antibodies on allograft acute rejection after cadaveric liver transplantation].

OBJECTIVE: To evaluate the effect of perioperative HLA antibody changes on acute allograft rejection in cadaveric liver transplantation. METHODS: Totally 134 patients received modified piggyback liver transplantation and enzyme-linked immunosorbent assay was performed for HLA antibody detection before and the 1, 7, 14 and 30 days after operation. B ultrasound-guided liver biopsy was employed for diagnosis of acute allograft rejection, and the perioperative changes of HLA antibodies were evaluated for their effect on allograft acute rejection. RESULTS: Of the 44 recipients with preoperative positivity for HLA antibodies, acute rejection occurred in 56.8% of the patients, as compared with 25.9% in those negative for HLA antibody (P=0.001). The patients who became positive for HLA antibody postoperatively had a rate of acute rejection of 60%, which was significantly higher than that in those persistently negative for HLA antibody (18.6%, P=0.003). CONCLUSION: HLA antibody positivity before transplantation may contribute to acute rejection episode in liver transplantation, and persistent posttransplant HLA antibody positivity is closely associated with the occurrence of acute rejection.

Adult↗

PubMed2006

[Application of implant-supported telescopic overdenture in edentulous cases].

OBJECTIVE: To evaluate clinical results of implant supported telescopic overdenture. METHODS: 21 patients with edentulous jaws underwent telescopic overdenture restoration. A total of 28 prostheses were fabricated. Of them, 13 were in the upper jaws, 15 in the lower jaws. Among 139 placed implants, 74 were Camcog, 28 IMZ, and 37 Frialit-2. The secondary crown was fabricated by electroforming technique and wax-lost cast method. Clinical examination and radiographs were conducted. Changes in the marginal bone level around the implants were evaluated with radiograph. The mean follow-up time was 26.5 months (range 12 - 39 months). RESULTS: This type of restoration could provide sufficient stability and maintain peri-implant hygiene easily. Peri-implantitis and prosthetic complications were not observed. Marginal bone around implants was stable. No implant was lost during the loading time. CONCLUSIONS: The preliminary clinical results of this research showed that implant supported telescopic overdentures were predictable for edentulous patients.

Aged↗

PubMed2005

Internal midface distraction in correction of severe maxillary hypoplasia secondary to cleft lip and palate.

BACKGROUND: Maxillary hypoplasia is a familiar deformity in patients with cleft lip and palate. A large amount of maxilla advancement is often needed to correct the severe deformity, but local soft-tissue scars around the maxilla restrict maxilla advancement and increase the relapse rate. By gradually lengthening both the bones and the soft tissues, midface distraction can greatly increase postoperative stability and lower the relapse rate. METHODS: Ten patients with severe maxillary hypoplasia secondary to cleft lip and palate were treated with midface distraction using three kinds of internal distraction devices. Among them, six patients received an alveolar bone graft from the iliac crest during their Le Fort I osteotomy, and a bilateral sagittal split ramus osteotomy was performed simultaneously to push back the mandible in five patients with prognathia, to obtain a normal soft-tissue profile and occlusal relationship. RESULTS: Successful maxillary advancements ranging from 5 to 15 mm were measured from preoperative and postoperative cephalograms. Patients' sella-nasion-point A angles increased from an average of 71.25 degrees preoperatively to 79.05 degrees postoperatively. Orthodontic therapies were adopted before and/or after midface distraction. After the consolidation period, dense new bone was found to have formed in the distraction gap. During the follow-up period, the position of the maxilla and the final occlusal relationship were stable and acceptable, and no obvious relapses were seen. CONCLUSION: Midface distraction is an ideal choice for the correction of severe maxillary hypoplasia secondary to cleft lip and/or palate.

Adolescent↗

PubMed2005

[Repair of orbital defects with implant-retained prostheses].

OBJECTIVE: To evaluate the clinical result of using osseointegrated implants to repair removable orbital prostheses in repairing orbital defects. METHODS: Two patients with orbital defects caused by orbital tumor were treated. Each of them got 4 implants. After average 6 months, we performed the secondary operation. After 7 weeks, we took impressions to make the implant-retained prostheses. The magnetic attachment was adopted. The prostheses were made of polysiloxane material (Factor II, Lakeside, Ariz). RESULTS: Both of the patients got the successful facial prostheses and were followed up 2 and 8 years respectively. All the implants were integrated well. There were no apparent inflammatory reactions in the soft tissue around percutaneous implants. The patients were satisfied with the facial appearance. CONCLUSION: Implant-retained orbital prostheses are safe and effective in repairing orbital defects.

Adult↗

PubMed2005

[Retrospective analysis of maxillary sinus augmentation for endosseous implants].

OBJECTIVE: To determine the long-term clinical outcome and predictability of the maxillary sinus augmentation procedure. METHODS: Seventy-four patients underwent 100 sinus bone graft procedure and 206 implants were placed. The patients were followed up for 1-9 years, with an average of 3.46 +/- 1.65 years after implant placement. RESULTS: The 5-year cumulative survival rate (CSR) of implants was 92.28%. Only 8 implants failed and no sinusitis occurred. CONCLUSIONS: Sinus bone graft is an adjunctive procedure with a predictable outcome in patients with severely atrophied posterior maxilla.

Adolescent↗

PubMed2004

[Study on repairing injured middle brain by Schwann cells transplantation].

OBJECTIVE: To explore the ability of grafted Schwann cells to promote restore of injured neurons in rat. METHODS: Schwann cells labeled by BrdU in vitro transplanted into rat middle brain area prior to injure with electric needle stimulus. Immunohistochemistry and image analyzer were used to investigate the expression of BrdU and GAP-43 as well as quantitative analysis respectively. RESULTS: BrdU positive cells could be identified for up to 8 months and the number increased about 15%, which mainly migrated toward injured ipsilateral cortex. The GAP-43 expression reached its peak one month after transplantation and was significant compared with control group (P < 0.05). CONCLUSION: The transplantation of Schwann cells could promote the restoration of injured neurons.

Animals↗

PubMed2004

[Immediate loading of dental implants in partialful edentulous and edentulous jaws].

OBJECTIVE: To investigate the clinical feasibility and technical characteristics of immediate loading and to access the short-term clinical results of treatment. METHODS: This study included 3 completely edentulous patients and 24 patients who were partially edentulous from March 1999 to December 2003. 21 implants were immediately loaded and provided support for mandibular overdenture for 3 fully edentulous patients. 30 implants were placed in 21 partially edentulous patients and implants were immediate loaded in edentulous mandibular providing support for fixed provisional prosthesis within 6 months. Then, metal-ceramic crowns were completed. All patients were followed up by 1, 3, 6, 12 months and the patients were checked every 12 months. RESULTS: A total of 42 implants were loaded immediately. From March 1999 to December 2003, no implants were lost during follow-up (range 3 to 49 months, mean of 28 months). No infections, nerve or sinus damage or other sequelae occurred. No implants exhibited peri-implant radiolucencies. Moreover, immediate loading seems to increase the ossification of the alveolar bone around endosseous implants. Patients were satisfied with the treatment. CONCLUSIONS: The data and the experience described in this study indicate that immediate loading with restorations using appropriate surgical and restorative techniques can predicate the completely edentulous and partially edentulous mandible in some cases. Further study is needed to determine the long-term result of immediately loaded implants.

Adult↗

PubMed2004

[Using platelet-rich plasma (PRP) to improve bone regeneration in implant bone defect].

OBJECTIVE: To evaluate the result of bone regeneration due to using PRP in combination with beta-TCP in bone defect adjacent to oral implantation. METHODS: Ten patients (6 males, 4 females, with an average age of 49.6 years) participated in this study. Seven of them underwent maxillary sinus augmentations, and 3 underwent GBR for peri-implant bone defects. PRP + beta-TCP was used in 4 cases and beta-TCP in other 6 as control. X-ray examinations were carried out prior to operation and in 1 week, at 3 months, 6 months after operation. After 4 - 6 months, 3 biopsy specimens were obtained at the time of the second stage operation in each group. RESULTS: Bone grafts healed well without any infection in all cases. Radiographs showed that bone grafts integrated together with the bone. The histological result showed that new bone was formed among particles of beta-TCP in both groups, but in PRP + beta-TCP group denser and better arranged woven bone was observed, and more new bone was formed into the micropores of the particles. CONCLUSIONS: The result in this study implied that PRP in combination with beta-TCP can improve bone regeneration in bone defect adjacent to oral implantation.

Adolescent↗

PubMed2003

Distraction osteogenesis in correction of micrognathia accompanying obstructive sleep apnea syndrome.

To evaluate the effect of distraction osteogenesis in correction of micrognathia accompanying obstructive sleep apnea syndrome, a total of 28 patients with different severities of obstructive sleep apnea syndrome underwent mandibular distraction osteogenesis. A total of 51 distraction devices were placed for bilateral distraction in 23 patients and for unilateral distraction in five patients. The mean age of patients was 21.2 years (range, 3 to 60 years). Eleven patients had micrognathia accompanying obstructive sleep apnea syndrome secondary to bilateral temporomandibular joint ankylosis, and 10 patients had micrognathia accompanying obstructive sleep apnea syndrome secondary to unilateral temporomandibular joint ankylosis. Three patients had developmental micrognathia accompanying obstructive sleep apnea syndrome. The other four patients had micrognathia and concomitant obstructive sleep apnea syndrome induced by trauma, infection, or tumor resection. Each patient had been evaluated preoperatively and postoperatively with cephalometry and polysomnography. Mandible advancement ranged from 9 to 30 mm (average, 20.4 mm) and was successfully achieved after distraction. Fine new bone formed in the distraction gap when the distraction devices were removed 3 to 4 months after distraction was completed. No infection or other complications occurred in any patients. Complete curative effects were achieved in nine severe, six moderate, and eight mild obstructive sleep apnea syndrome patients after distraction, and the other five patients had been improved to the mild level. After distraction was completed, the posterior airway space was increased on average from 4.6 mm to 12.5 mm and the sella-nasion-point B angle was increased on average from 66 degrees to 75 degrees on cephalometric studies. The polysomnographic examination showed that the apnea hypopnea index was lowered on average from 58.0 to 3.15, and the lowest oxygen saturation was increased on average from 77 percent to 90.3 percent after distraction was completed. The follow-up period was 3 to 61 months (average, 18.1 months). The curative effect was stable and no relapse occurred. Therefore, the authors conclude that mandibular distraction osteogenesis is an effective method for correcting micrognathia accompanying obstructive sleep apnea syndrome. Compared with other current routine surgical procedures, it has many advantages, such as low risk, simple manipulation, high curative rate, low relapse rate, and stable result. It is presently the most effective method for the treatment of this difficult and complicated disorder.

Adolescent↗

PubMed2003

[Clinical study of immediate implant].

OBJECTIVE: To evaluate the clinical result of immediate implant. METHODS: 32 cases underwent immediate implant surgery for 59 implants simultaneously when the teeth or roots extracted. 55 implants were placed with bone grafts or bone substitutes. The second stage operation were performed in the sixth month and ceramic crown were fixed in the seventh to eighth month postoperatively, the follow up were mean 39 months. RESULTS: One implant was lost. Bone resorption of alveolar crest was observed in 4 implants. Mean resorption was 2 mm. CONCLUSIONS: The result of immediate implant is predictable, the advantages are avoiding the alveolar bone resorption after teeth extraction, implant could be placed in an ideal position; less operation trauma, good esthetics results.

Adult↗