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Biomedical subjects

Yaguang Zeng

Publications and source records attributed to Yaguang Zeng.

3 recordsLinked to original sources

Photoacoustic and ultrasonic coimage with a linear transducer array.

A technique is developed to simultaneously acquire ultrasound and photoacoustic (PA) images based on a linear transducer array. The system uses conventional ultrasound for rapid identification of potential targets. After a target is identified, the ultrasound echo and PA signals can be simultaneously obtained with optimized excitation and a signal collection sequence. The corresponding ultrasound impedance and optical absorption images are reconstructed with a phase-controlled algorithm. The approach can effectively reduce the artifacts associated with a conventional filter backprojection algorithm used in PA imaging by linear scanning. The technique provides a new approach for practical applications.

Algorithms↗

Photoacoustic imaging with deconvolution algorithm.

The impulse response of the ultrasonic transducer used for detection is crucial for photoacoustic imaging with high resolution. We demonstrate a reconstruction method that allows the optical absorption distribution of a sample to be reconstructed without knowing the impulse response of the ultrasonic transducer. A convolution relationship between photoacoustic signals measured by an ultrasound transducer and optical absorption distribution is developed. Based on this theory, the projection of the optical absorption distribution of a sample can be obtained directly by deconvolving the recorded PA signal originating from a point source out of that from the sample. And a modified filtered back projection algorithm is used to reconstruct the optical absorption distribution. We constructed a photoacoustic imaging system to validate the reconstruction method and the experimental results demonstrated that the reconstructed images agreed well with the original phantom samples. The spatial resolution of the system reaches 0.3 mm.

Acoustics↗

Fast photoacoustic imaging system based on 320-element linear transducer array.

A fast photoacoustic (PA) imaging system, based on a 320-transducer linear array, was developed and tested on a tissue phantom. To reconstruct a test tomographic image, 64 time-domain PA signals were acquired from a tissue phantom with embedded light-absorption targets. A signal acquisition was accomplished by utilizing 11 phase-controlled sub-arrays, each consisting of four transducers. The results show that the system can rapidly map the optical absorption of a tissue phantom and effectively detect the embedded light-absorbing target. By utilizing the multi-element linear transducer array and phase-controlled imaging algorithm, we thus can acquire PA tomography more efficiently, compared to other existing technology and algorithms. The methodology and equipment thus provide a rapid and reliable approach to PA imaging that may have potential applications in noninvasive imaging and clinic diagnosis.

Acoustics↗