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Biomedical subjects

Y Zubery

Publications and source records attributed to Y Zubery.

At least 19 recordsLinked to original sources

[Immediate implants without primary stabilization in the molar region].

Primary stabilization of implants was always considered a prerequisite for success. However, in many cases of extraction of molar teeth, the size of the extraction socket is larger than the widest implant available. A technique for immediate replacement of molar teeth with implants placed in bone allograft or xenograft is described. Following careful extraction of the tooth and thorough debridement of the socket, the bone graft is placed and carefully condensed. The implant carrier screw is slightly released and the implant inserted with careful rotation. Following placement of the cover screw the socket is covered with a membrane and primary closure of soft tissue is achieved. Case 1 Tooth 47 with primary endodontal periodontal-endodontal lesion is extracted and immediately replaced with a 6 mm implant. Six months later following second stage surgery, the implant is progressively loaded for one year and the final crown is placed. Case 2 Tooth 37 with a history of repeated abscesses, a perforation to the furcation area is diagnosed and the tooth extracted. The socket was filled with bovine bone xenograft and a 6 mm implant placed. Six months later the implant was evaluated and second stage surgery performed. Following six months with temporary crown, a final porcelain crown was fabricated. This technique can be used in cases where primary stabilization of immediate implants cannot be achieved and there is a demand for a single surgical procedure. A careful surgical protocol will yield predictable results and will preserve hard and soft tissues following tooth extraction.

Adult↗

Immediate loading of modular transitional implants: a histologic and histomorphometric study in dogs.

Modular Transitional Implants (MTI) are made from pure titanium and are used to support fixed provisional restorations during the osseointegration of definitive implants. This study histologically examined the jaw response to loaded MTIs in the dog mandible. Three implants were inserted transmucosally into each side of the mandible in 3 dogs. Stability was examined using a Periotest. Anterior and posterior implants were splinted using a cemented acrylic resin fixed partial denture to allow immediate loading. The middle implant remained unloaded and was used as a control. Dogs were sacrificed 11 to 12 weeks after implantation, and tissue blocks containing the implants were removed. Histologic examination showed that 10 of the 18 implants had good bone-to-implant contact, with the percentage of bone contacting the threaded portion of the implant varying from 30% to 65%. There was no statistical difference (p > 0.1) in percentage of bone-to-metal contact between loaded and unloaded implants. Six implants were entirely surrounded by connective tissue with or without inflammation; two implants were lost during the study. The success rate did not differ between loaded and unloaded implants. In the successful implants trabecular bone made good contact with the implant, forming supporting struts. There was bone remodeling in some bone-to-metal contact areas. It is believed that success was mainly influenced by the initial bone density at the implant site and by the uncontrolled load that the animals applied to the implants during the early healing stage.

Animals↗

Bone resorption caused by three periodontal pathogens in vivo in mice is mediated in part by prostaglandin.

Gingival inflammation, bacterial infection, alveolar bone destruction, and subsequent tooth loss are characteristic features of periodontal disease, but the precise mechanisms of bone loss are poorly understood. Most animal models of the disease require injury to gingival tissues or teeth, and the effects of microorganisms are thus complicated by host responses to tissue destruction. To determine whether three putative periodontal pathogens, Porphyromonas gingivalis, Campylobacter rectus, and Fusobacterium nucleatum, could cause localized bone resorption in vivo in the absence of tissue injury, we injected live or heat-killed preparations of these microorganisms into the subcutaneous tissues overlying the calvaria of normal mice once daily for 6 days and then examined the bones histologically. We found that all three microorganisms (both live and heat killed) stimulated bone resorption and that the strain of F. nucleatum used appeared to be the strongest inducer of osteoclast activity. Treatment of the mice concomitantly with indomethacin reduced but did not completely inhibit bone resorption by these microorganisms, suggesting that their effects were mediated, in part, by arachidonic acid metabolites (e.g., prostaglandins). Our findings indicate that these potential pathogens can stimulate bone resorption locally when placed beside a bone surface in vivo in the absence of prior tissue injury and support a role for them in the pathogenesis of bone loss around teeth in periodontitis.

Alveolar Bone Loss↗

Effect of non-erupted 3rd molars on distal roots and supporting structures of approximal teeth. A radiographic survey of 202 cases.

Root resorption of 2nd molars in proximity to non-erupted 3rd molars has been widely reported. The purpose of this study was to determine the prevalence of root resorption in second molars adjacent to non-erupted third molars. Its association to age and gender of the patient, location and inclination of the non-erupted third molar and to distal bone support of the 2nd molars was analyzed. A radiographic survey of 202 periapical radiographs taken in patients with clinically missing third molars was conducted. 3 examiners independently evaluated the radiographs and only those cases where at least 2 observers agreed were included in this report. Statistical analysis was performed on 186 radiographs. Associations were analyzed with the Pearson chi 2 test. Radiographic evidence of root resorption was found in 45 2nd molars (24.2%) of which 12 (6.5%) showed moderate to complete root resorption. Non-erupted tooth apical position and mesio-inclination of 60 degrees or more relative to the distal root of the second molar were significantly associated with root resorption (p = 0.01368 and p = 0.0194, respectively). Resorption was positively associated with age of patient (p = 0.00606). These results may support early extraction of impacted 3rd molars especially in cases with a mesio-angulation of 60 degrees or more and an apical location in proximity to the distal root of the 2nd molar.

Adolescent↗

Orthodontic tooth movement following guided tissue regeneration: report of three cases.

This report presents three patients with advanced adult periodontitis and in which orthodontic tooth movement was performed subsequent to guided tissue regeneration procedures. Clinical follow-up showed a mean 3.3-mm attachment gain in the deepest preoperative probing depth sites, and radiographs revealed bone fill following guided tissue regeneration procedures with resorbable and nonresorbable membranes, with and without the use of demineralized freeze-dried bone allograft. Orthodontic tooth movement into the regenerated areas was successful. The feasibility of orthodontic tooth movement following successful regenerative procedures is discussed.

Adult↗

Lack of evidence for hypophosphatasia as a factor in the pathogenesis of early-onset periodontitis.

Hypophosphatasia, an inheritable metabolic disorder affecting calcification, has been shown to have various oral manifestations. Recently, it was suggested that it may serve as a predisposing factor in the pathogenesis of early-onset periodontitis. The present study was designed to examine the frequency of hypophosphatasia among patients with juvenile periodontitis and rapidly progressive periodontitis. Eighteen patients, nine females and nine males (age 19-37 years, mean 23.2 years), were included in this study. Venous blood and urinary samples were collected and assayed for alkaline phosphatase and urinary phosphoethanolamine. Mean alkaline phosphatase levels (109 +/- 35 IU/L) were within the normal limits for all patients except one who exhibited slightly lower than normal values. Urinary phosphoethanolamine, a typical marker of hypophosphatasia, was absent from all specimens, which rules out the possible diagnosis of such disorder in these patients. Until more information is available, the role of hypophosphatasia as a predisposing factor in early-onset periodontitis is yet to be established.

Adult↗

Two approaches to the treatment of true combined periodontal-endodontal lesions.

Periodontal endodontal lesions present a difficult diagnostic and treatment challenge to the clinician and treatment often requires a combined therapeutic effort. Both endodontal and periodontal surgical procedures may be indicated for access and treatment of these lesions. This case report presents an early onset periodontitis patient with bilateral periodontal-endodontal lesions on mandibular first molars. Treatment included apical surgery followed by repeated scaling and root planing on one tooth and root canal obturation followed by a periodontal bone grafting procedure on the other. Both procedures resulted in clinical attachment gain as well as radiographic evidence of alveolar bone gain. This case report once again demonstrates that proper diagnosis followed by removal of etiologic factors and nonsurgical therapy or periodontal regenerative procedures can restore health and function in cases of severe attachment loss.

Adult↗

An in vitro study of the characteristics of a computer-aided radiographic evaluation (CARE) system for longitudinal assessment of density changes.

In recent years, several systems for computerized analysis of radiographs have been introduced, most of which use digital conversion of the image followed by subtraction of consecutive images to assess changes. This paper introduces a computer-based qualitative and quantitative radiographic evaluation system based on the CADIA algorithm. Problems associated with computerized radiographic analysis are discussed and evaluation criteria for this type of system are suggested. These criteria include evaluation of system noise and threshold setting, reproducibility, and establishment of the system working curve (validity). The CARE system noise ranged from a -10 to +10 CADIA value and the threshold was set on 13 for all measurements. The reproducibility was high, both for the radiographic technique and for repeated measurements. The working curve was established and showed the system's ability to detect small density changes of 0.048 O.D. which corresponds to 0.27 mm of aluminium thickness or compact bone equivalent. The linear range of the curve was between 0.7 and 1.8 O.D. By controlling the exposure parameters it was possible to work within the linear range of the curve. Based on these evaluation criteria, the CARE system can be used to quantitatively evaluate small density changes on sequential radiographs for early detection of caries and periodontal disease.

Alveolar Bone Loss↗

Histologic assessment of a contiguous autogenous transplant in a human intrabony defect. A case report.

Increased blood supply, vital bone marrow cells, and minimal mobility may play a significant role in the success of osseous grafts, and are characteristics of the bone swaging grafting technique. As in all autogenous grafts, the risk of disease transmission is minimal. Previous reports of clinical success raise questions as to the type of tissue response to this procedure. This case report examines 8 months radiographic and histologic results of a clinically successful bone swaging graft.

Adult↗

Periodontal surgical techniques used to conserve maxillary anterior esthetics.

The maxillary anterior region presents a difficult and unique therapeutic challenge in the treatment of periodontal disease. The periodontist should use therapeutic procedures to prevent or minimize esthetic problems, such as increased tooth length and loss of interdental papilla, without compromising the main goals of periodontal treatment. This article presents various periodontal treatment modalities that can be used in the anterior maxillary area with acceptable esthetic results. A better understanding of the problem, the treatment steps, and the various options available may improve the communication between the general practitioner and the periodontist, producing satisfactory long-term results.

Cuspid↗

The efficacy of Plax prebrushing rinse: a review of the literature.

Removal of bacterial plaque is a prerequisite to the prevention and control of periodontal disease. In highly motivated patients, it is possible to control plaque successfully by mechanical means. Because most patients lack sufficient motivation and skill to perform effective plaque control on a regular basis, use of antimicrobial chemical agents is essential to gingival health. In 1985, Plax, a prebrushing oral rinse, was introduced. The manufacturer claims that the solution acts as a detergent that removes some bacterial plaque and loosens the remainder for easy removal by toothbrushing. A review of current dental research related to this claim is presented. The data provided do not support the use of Plax dental rinse as part of an oral hygiene program.

Benzoates↗

Inhibition of plaque formation and gingivitis in beagle dogs by topical use of a degradable controlled-release system containing chlorhexidine.

The in vivo efficacy of a newly-developed dental application of a film-forming, chlorhexidine-containing system was examined in beagle dogs. A self-disintegrating film-forming solution was applied three times weekly to the dentitions of 7 out of 13 dogs, which were fed a soft-food diet. Plaque accumulation (Plaque Index) and gingival inflammation (Gingival Index) were recorded at one, two, four, six, and eight weeks. The local delivery of low-dose chlorhexidine to dogs significantly inhibited gingivitis and plaque formation. It is concluded that the dental application of a film-forming system may be a preferable method of periodontal disease prophylaxis, and may enhance supragingival plaque control in areas of isolated periodontal problems associated with obvious local predisposing factors.

Animals↗

The management of soft tissue defects using the "gingival shaving" technique.

A simple, effective technique is described for the correction of unfavourable gingival contour during post-surgical or pre-prosthetic procedures. Termed the "gingival shaving technique", it is conducted with high-speed course diamond burs. Results are relatively rapid and predictable, especially in cases where esthetics are most desirable. The technique can be performed by the periodontist or prosthodontist, and can be repeated until satisfactory gingival contour is achieved. Case selection, careful preparation, and post treatment management and care are essential for success.

Dental High-Speed Technique↗

Advanced periodontal disease and development of anterior open bite. A case report.

Severe anterior open bite in adults is often both functionally and esthetically unacceptable. The treatment usually consists of a combined orthodontic and surgical correction. The stability of open bite treatment results is often poor. The case presented is of marked anterior open bite in a previously normal bite patient with advanced periodontal disease. An etiology for the development of this condition is suggested and a successful treatment described.

Aged↗

Multiple therapy approach to juvenile periodontitis: a case report.

Various therapeutic techniques for the treatment of juvenile periodontitis are reported in the literature, with occasional contradictory results. One of the reasons for the contradictory results may be differences in patient selection and/or response to treatment. The following report describes the results of various treatment modalities, in different sites in the same individual, on localized juvenile periodontitis.

Adult↗