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Biomedical subjects

Y Yoshii

Publications and source records attributed to Y Yoshii.

At least 145 records · Page 8Linked to original sources

Biopsy and cytology in the diagnosis of early gastric cancer: 10-year experience with direct vision techniques at a Japanese institution.

The results of direct vision biopsy and cytology for the diagnosis of early gastric cancer during the periods from 1964 to 1969 and from 1970 to 1974 were compared. From 1964 to 1969 the diagnostic accuracy of gastric biopsy was 94.7% at the initial examination and 97.3% in the final diagnosis, while washing cytology under direct vision gave a diagnostic accuracy of 83.0% at the first washing and 93.3% in the final cytologic diagnosis. Because of such a high yield of gastric biopsy, it was the procedure of the first choice from 1970 to 1974, giving a diagnostic accuracy of 96.7% at the initial examination and 99.4% in the final biopsy diagnosis with only one suspicious case. The cytologic examination by brushing has, therefore, become supplementary to biopsy in cases where a stenosis proximal to a tumor obscures the definitive tissue.

Biopsy↗

[Studies on the prognosis of Moyamoya disease--diagnostic capability of CT scanning].

The author evaluated the diagnostic values of CT-Scanning on 20 cases of Moyamoya. No visualization of Moyamoya vessel was obtained, even after enhancement, but the author could differentiate 3 types of atrophic findings; normal pattern, cortical atrophic pattern, and wedged pattern. Futhormore, there was a considerable correlation between these findings and angiographic findings. CT-Scanning dose not have a diffinite diagnostic value in Moyamoya but is a very effective examination for the follow up study in Moyamoya.

Adult↗

Clinical and radioisotopic follow-up study of 'Moyamoya'.

24 children with 'moyamoya' had average follow-up periods of 5 years and 9 months. The following factors were noted to influence the prognosis for mental function: early onset, repeated transient ischemic attacks followed by residual neurological deficit, symptoms suggesting bilateral or dominant hemispheric lesions, and angiographically widespread occlusion. Futhermore, radioisotopic procedures could replace angiography for follow-up studies of patients with Moyamoya.

Adolescent↗

[Cerebellar hemangioblastoma with multiple aneurysms].

We have reported a case of cerebellar hemangioblastoma in a 50 year-old Japanese female in which bilateral kidney and ovarian cysts, adrenal adnomatus hyperplasia, and erythrocytosis were observed. Futhermore, an aneurysm not initially observed was detected by cerebral angiography done 23 months after tumor extirpation. We have evaluated the relationship between cerebellar hemangioblastoma and concurrent multiple aneurysms with reference to reported cases.

Cerebellar Diseases↗

[Characteristics of brain scintigraphy in pediatric age group and its diagnostic value in brain tumors (author's transl)].

The diagnostic value of brain scintigraphy in intracranial diseases has been well recognized. Numerous reports have appeared in the literature concerning its use in adult cases. The reports dealing with pediatrics cases, however, are quite limited in number. The major factors limiting such studies in children may be considered as follows; (1) infratentorial tumors are common in this age group, in which its diagnostic accuracy has been believed to be quite low, (2) problems of exlosing children to radiation and (3) difficulty in keeping children in one position for a considerable length of time. These difficulties were almost overcome by the use of 99m Tc with a very short half life and a gamma camera, resulting in increased application of this procedure to children. The purpose of this report is to analyse and discuss the scintigraphical characteristics in children and evaluate the diagnostic value in brain tumors. The subjects consist of 199 non-tumoral cases and 53 cases of verified brain tumors. Following conclusions were obtained: (1) Aging changes are noted in normal brain scintigrams of children. One of them is related to the mode of visualization of the basal structures in lateral views. The cranial base appears to be flat before the age of 4 years. A triangular process then appears at the cranial base, approaching that of adult over the age of 10 years. Another change is related to appearance of the temporal and occipital muscles over the cranial vault and the posterior fossa. This becomes apparent about the age of 7 years and produces such masking effects as to interfere with diagnosis in this region over the age of 10 years. (2) The choroid plexus are visualized in about 10% of cases. (3) In brain tumor cases, the detecting rate is 93% in gliomas, and 73% in non-gliomatous tumors. It is particularly low in congenital tumors.

Adolescent↗

Glycylprolyl beta-naphthylamidase activity in human serum.

Glycylprolyl beta-naphthylamidase activities in sera from 40 normal subjects (18-81 years) were: 22.6 +/- 0.9 (S.E.) (11.8-38.2) I.U./1 serum at 37 degrees C. The enzyme activities did not differ significantly with age between the younger group under 40-years-old and the older group over 40-years-old. Males, especially under 40-years-old, had slight but significantly higher activities than females. The levels were decreased in patients with gastric cancer. The levels were elevated in patients with hepatobiliary diseases, and had significant correlations with the results of the serum tests in hepatic diseases such as glutamic-oxaloacetic transaminase, glutamic-pyruvic transaminase, alkaline phosphatase and total bilirubin, but had no correlation with serum lactate dehydrogenase. In cellulose acetate electrophoresis, normal sera had a single peak at the beta-globulin region, but the sera in hepatitis or liver cirrhosis showed not only an increase in the normal peak at the beta-globulin region but also the appearance of the other one or two new peaks in the alpha1 and alpha2-globulin regions.

Acute Disease↗