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Biomedical subjects

Y Wolloch

Publications and source records attributed to Y Wolloch.

At least 37 records · Page 2Linked to original sources
PubMed1993

Carcinoma of the colon in youngsters: a report of three cases.

Three youngsters aged 12, 16, and 18 years underwent surgery for carcinoma of the colon, a very rare occurrence in this age-group. In all three patients the prominent feature was a marked delay in diagnosis and treatment, as reflected in the advanced pathological stage of the tumors (Dukes' C and D). An increased awareness of the possible occurrence of this type of tumor in young patients, and the resultant earlier diagnosis, are the only means for improving the prognosis.

Adenocarcinoma↗
PubMed1993

Primary appendiceal neoplasms.

A retrospective review of the files of 1,740 appendectomies performed during a 10-year period disclosed 13 patients (0.7%) with primary appendiceal tumors. Adenocarcinoma of the appendix was diagnosed in 6 patients (0.3%), which is a two- to four-fold higher incidence than reported in the literature. The other seven patients had benign tumors and only appendectomy was performed. The female to male ratio of adenocarcinoma was 5:1. All six adenocarcinoma patients, classified histologically as Dukes' B stage, underwent right hemicolectomy, and were disease free following a mean follow-up of 35 months. The results of our policy, also recommended by others, confirmed the benefit of right hemicolectomy in all patients with confirmed primary appendiceal carcinomas.

Adenocarcinoma↗
PubMed1992

[Rectosigmoid carcinoma in an adolescent girl].

Carcinoma of the colon and rectum is very rare in childhood and adolescence. We describe a 16.5-year-old girl with rectal bleeding and constipation. She had been treated symptomatically for 6 months without being properly examined. Only with onset of weight loss was rectal examination performed. After workup a diagnosis of locally advanced carcinoma of the rectosigmoid with multiple lung metastases was reached. From review of the literature and our own case, it seems that the unfavorable prognosis in young patients is mainly due to lack of awareness of such a possibility, resulting in delayed diagnosis and treatment. An additional factor is the invasive nature of most colon cancers in this age group.

Adolescent↗
PubMed1991

Prospective comparative study of magnetic resonance imaging versus transrectal ultrasound for preoperative staging and follow-up of rectal cancer. Preliminary report.

The efficiency of magnetic resonance imaging (MRI) and that of transrectal ultrasound (TRUS) were compared in preoperative staging of 15 patients with rectal cancer and in postoperative follow-up of 12 patients. Thirteen of the 15 patients evaluated for preoperative staging were operated on. Preoperative staging and pathologic finding were identical in 11 patients (84.6 percent) examined by TRUS and in 10 patients (76.9 percent) examined by MRI. Recurrent cancer was detected in 3 of 12 patients in the follow-up group. MRI was able to diagnose correctly 10 of 12 patients (83.2 percent), one patient was misdiagnosed, and in one patient the MRI could not distinguish between fibrous tissue and recurrent cancer. TRUS diagnosed correctly only 5 of 12 patients (41.6 percent). One was falsely diagnosed, and, in 6 patients (50 percent), this examination could not differentiate between fibrous tissue and recurrent tumor. According to our results, both MRI and TRUS have a place in the preoperative staging of patients with rectal cancer. The main differences between the two methods were in the differential diagnoses of fibrous tissue and recurrent cancer. MRI being more specific in detection of recurrence.

Aged↗
PubMed1991

B lymphocyte changes induced by peri-operative blood transfusions and surgery in patients with colorectal cancer.

Seventy patients with Duke's C adenocarcinoma scheduled to undergo surgery were divided into two groups, those who received no peri-operative transfusion (Group I, 26 patients) and those who received an average of 2.1 units of packed red blood cells per person peri-operatively (Group II, 44 patients). Immunological parameters were tested 1 week before and 1 and 5 weeks after surgery in order to determine the influence of the transfusion of these parameters. Comparison of the mean values obtained before operation with those obtained one week post-operatively revealed a significant change in the number of B cells (P = 0.014), with a decrease in Group I and an increase in Group II, which was seen to persist for the mean values obtained 5 weeks after surgery. The higher rates of recurrence and the lower rates of survival reported in patients who received transfusion may be related to an as yet unidentified role of B cells or a subpopulation in the immune system, manifested in the suppression of activity of those components responsible for destroying micrometastases. In relation to the site of the tumor no definite conclusions can yet be drawn as to the prognostic importance of our findings concerning the immunological parameters.

Adenocarcinoma↗
PubMed1989

Comparative study for preoperative staging of rectal cancer.

A comparative study of preoperative evaluation of rectal cancer is presented. Sixty-eight patients with rectal cancer were examined digitally and by computerized tomography and transrectal ultrasound. Preoperative staging was compared with pathologic findings at surgery. Digital examination and transrectal ultrasound were accurate in 82.8 and 76.2 percent, respectively and were superior to CT, which was accurate in 65.5 percent of cases for assessment of rectal wall invasion. All three modes play a role in preoperative assessment, but digital examination and rectal ultrasound appear to be more effective.

Adult↗
PubMed1989

Phenol sclerotherapy for hydrocele: a study in 55 patients.

Sclerotherapy with 2.5% phenol solution was used to treat 63 hydroceles in 55 patients with a mean age of 69 years. In 51.6% of the patients (32 hydroceles) 1 treatment was sufficient, while 2 treatments were necessary in 25.8% (16 hydroceles), 3 in 13% (8 hydroceles) and 4 in 8% (5 hydroceles). One patient required 7 injections. Treatment was unsuccessful in 1 patient in whom a local allergic reaction developed. Only 1 patient complained of pain, and other complications were rare and mild. On the basis of this experience we concluded that sclerotherapy with phenol 2.5% is a painless, highly effective, safe and economical procedure that permits one to avoid an operation, anesthesia and hospitalization. Its use is warranted in adults and particularly in the elderly.

Adult↗
PubMed1989

Segmental portal hypertension and polycythemia vera.

A patient known to have polycythemia vera developed recurrent melena and was found to have bleeding gastroesophageal varices. Selective superior mesenteric angiography suggested splenic vein thrombosis. Splenectomy led to the disappearance of the varices with no subsequent recurrence of bleeding. We believe this to be the first fully described case of polycythemia vera associated with segmental portal hypertension, and propose that polycythemia vera patients may develop "silent" segmental portal hypertension and that this should be taken into consideration when treating them.

Humans↗
PubMed1988

Local recurrence after low anterior resection using the EEA stapling device.

Fifty-five patients underwent curative stapled low anterior resection for rectal adenocarcinomas located 5 to 15 cm from the anal verge. Two patients (3.7 percent) died postoperatively. The mean follow-up for the remaining 53 patients was 40 months. Local recurrence was diagnosed in 17 patients (32 percent), in most (88 percent) within the first two years after surgery. Most local recurrences appeared in patients classified as Dukes' C1 and C2 but, surprisingly, no significant difference was found between rectal tumors of high and low location as regards recurrence. The high rate of recurrence in this series may be attributable to the large number of patients with advanced tumors, and poorly differentiated carcinoma, or both.

Adenocarcinoma↗
PubMed1988

Neutropenic enterocolitis. Case report.

Early recognition and adequate treatment of neutropenic enterocolitis, a life-threatening complication of aggressive chemotherapy for leukemia, lymphoma or other malignancy, may offer a favorable outcome. Three cases are presented, including the first reported occurrence in a child with osteogenic sarcoma. Two patients were treated surgically and the third conservatively.

Adult↗
PubMed1987

A simple method for palliative diversion of the bile in patients with obstructive jaundice due to perihilar tumors.

A palliative procedure for diversion of bile in patients with obstructive jaundice due to nonresectable perihilar tumors is described. The procedure is accomplished by creating an internal fistula between a bile duct and the gallbladder and an anastomosis of the gallbladder to the jejunum. The procedure is simple and bleeding of the hepatic parenchyma is readily controlled and subsequently, there is a rapid fall in the bilirubin level.

Bile Ducts↗
PubMed1987

Osteoclast-type giant cell tumor of the pancreas. Case report.

Local resection of a 1200 g, apparently inoperable pancreatic mass was performed on an elderly woman. Because she survived for more than 6 years without recurrence or metastases, the specimens were reviewed. They were compatible with giant cell tumor of osteoclast type. Correct diagnosis of this unusual tumor is important because of its seemingly favorable prognosis.

Aged↗
PubMed1986

Histopathologic high risk factors influencing the prognosis of patients with early breast cancer (T1N0M0).

A retrospective study of 78 women with early breast cancer was undertaken with the aim of detecting histopathologic risk factors that would influence the prognosis of these patients. Histologic tumor type, nuclear grade of tumor, tumor margin, and lymphoid infiltration near the tumor as well as blood vessel invasion and lymphatic tumor emboli were evaluated. The overall 10 year survival rate was 79.2 percent. In correlating the aforementioned criteria against survival rate, it was found that the patients without any of the histopathologic risk factors had a 100 percent rate, whereas those with one risk factor had a 79 percent rate and those with two or more risk factors a 66 percent rate. Nuclear grade and lymphoid infiltration were found to have the highest significance in regard to recurrence and the mortality rate. The findings of this study suggest that in patients classified as having T1N0M0 disease without any of the histopathologic risk factors, operation is the only treatment indicated. Patients with one or more positive risk factors should receive adequate adjuvant therapy in order to increase their survival rate.

Actuarial Analysis↗