Endoscopic retrograde cholangiopancreatography in pediatric surgical biliary diseases.
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Biomedical subjects
Publications and source records attributed to Y Urakami.
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Peroral cholangiopancreatoscopy (PCPS) using a mother and babyscope was attempted in 30 cases and the duct systems were successfully inspected in 25 cases. This procedure should be useful in cases with biliary and pancreatic diseases if the bending system and biopsy channel of the babyscope can be improved. Peroral direct cholangioscopy (PDCS) using four kinds of forward-viewing small-caliber fiberscopes was successfully employed in 14 of 22 cases. These instruments have a biopsy channel as well as an air-supplying and an aspiration channel, so that a stone can be removed with a basket catheter under visual control. PDCS should become valuable therapeutically in bile duct diseases if the fiberscope can be improved.
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Up to now, surgery was the only possible treatment for choledochoduodenal fistulas, which are seen more often in Japan than in Europe. This paper presents the value and effect of endoscopic fistulotomy (EFT) as an alternative treatment in those cases. Parapapillary choledochoduodenal fistulas are abserved usually on the longitudinal fold of the papilla or on its oral side. The papillotome is inserted into the common bile duct through the orifice of the duodenal papilla, then the wall between its orifice and the fistula is cut to open widely the distal portion of the choledochus. EFT was performed successfully in 7 cases. The procedure led to a wide open stoma of the distal common bile duct with free bile outflow. Residual stones, a common occurrence in cases of parapapillary choledochoduodenal fistulas, may pass spontaneously after EFT or can be removed with a basket catheter. In cases of parapapillary choledochoduodenal fistula, EFT is a reliable method, especially in high-risk patients, and an alternative to surgical treatment.
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A new technuque of ERC(P) using a forward-veiwing fiberscope is described in details. By this procedure the position of the maximal bended tip of the instrument provides a more selective cannulation of the common bile duct, preventing the risk of pancreatic duct filling. The method was performed in 15 cases and succeeded in 12. ERCP, using this technique, can be performed after normal esophago-gastro-duodenoscopy. However, at present time it is not a routine procedure. Technical improvements on the instrument are necessary to facilitate the method.
A new endoscopic method, the peroral direct cholangioscopy (PDCS) is described. A prograde fiberscope of 8.8 mm diameter can be directly inserted, without using a second scope as a guide, into the biliary system after EPT (endoscopic papillotomy). The lumen of the common bile duct is observed entirely and exactly. The image is excellent. Also acessories may be inserted into the duct via the biopsy channel under direct control.
The value of ERCP in children is demonstrated on 3 cases. By using a usual duodenofiberscope (JF-B2), in 2 cases under general anesthesia and in one case after premedication with 1 ml Buscopan i.m., a similar technique is used as in adults. In congenital choledochal cyst only ERCP allowed the exact judgement of the distal part of the common bile duct and its relation to the pancreatic duct. Therefore, an exact preoperative diagnosis can be established. When duodenofiberscope will be more improved ERCP will also be possible in the newborn infant. Than the differential diagnosis of congenital biliary atresia, other congenital failures in infants causing jaundice and hepatitis in infant will be established endoscopically.
First experiences with duodenoscopic guided biopsy of the biliary and the pancreatic duct on 11 cases using a special designed forceps showed that this method gave good and representative results in the biliary duct and from the papilla. However, in the present stage of development guided biopsy from the pancreatic duct does not aid exact differential diagnosis of benign or malignant lesions. In 3 out of 4 cases with pancreatic cancer the histological diagnosis was false negative. The biopsy specimens are very small and need an exact preparation and great experience of the histologist. Cytologic criteria must be relied on more here as in other areas of the GI-tract. However, the criteria of malignancy rest not in the nature of the individual cell but in the manner of proliferation, namely the infiltration of the deeper layers. This is the advantage of guided biopsy compared to cytological examination. Complications of the method may be avoided by exact guiding of the forceps and by limiting the numbers of specimens.
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