Cytodiagnosis of HCG-secreting choriocarcinoma of the stomach. Report of a case.
Explore the source record for details and available documents.
Choriocarcinoma↗
Biomedical subjects
Y Uei
Publications and source records attributed to Y Uei.
Cytologic diagnosis of breast carcinoma with nipple discharge: special significance of the spherical cell cluster.
In order to investigate the cytologic characteristics of breast carcinoma in nipple discharge, 190 histologically proven cases of various breast lesions from 2,723 samples of nipple discharge were studied. The general criteria of malignancy as described for other organs applied also to the breast carcinoma cells. However, the breast carcinoma cells were generally smaller and less pleomorphic than those arising from other organs. In addition to the malignant features of individual tumor cells, the presence of a spherical cell cluster with a smooth rim was also an important finding suggestive of malignancy. The diagnostic rate of breast carcinoma increased significantly when the 190 cases were reexamined on the basis of the findings of this study.
Breast↗
Light and electron microscopic analysis of intranuclear inclusions in papillary adenocarcinoma of the lung.
The incidence and nature of intranuclear inclusions found in tumor cells of preoperative and postoperative cytologic, histologic and electron microscopic (EM) specimens were studied in 38 cases of papillary adenocarcinoma of the lung in order to assess the cytodiagnostic significance of these inclusions. The overall incidence of the intranuclear inclusions was 34%; the incidence was higher in the well-differentiated type of adenocarcinoma (48%). Four smear and four EM types of inclusions were recognized. Cytoplasmic invaginations (pseudoinclusions), single-membrane-bound inclusions, aggregates of 50-nm tubules and any combination of the above could be distinguished by EM. There was some correlation between the smear and EM types of inclusions. EM analysis suggests that intranuclear inclusions, except for pseudoinclusions, may be derived from the inner nuclear membrane. In routine cytology, the intranuclear inclusion is a good diagnostic marker for papillary adenocarcinoma of the lung.
Adenocarcinoma, Papillary↗
Cytologic features of peripheral squamous cell carcinoma of the lung.
Cytologic features of 32 peripheral squamous cell carcinomas of the lung were reviewed. Fine needle aspiration biopsy and curettage showed most of the tumor cells to be arranged in irregular cell fragments consisting of relatively small cells with scanty cytoplasm. They possessed round to oval nuclei with coarsely granular chromatin, and some had large, prominent nucleoli. Keratinization was usually observed in small numbers of scattered cells, and a nuclear streaming arrangement was noted in some areas. When both keratinization and streaming arrangements were absent, correct subtyping was impossible (12 cases). These cytologic features were different from those of 31 hilar squamous cell carcinomas studied as controls; there many carcinoma cells showed keratinization, and small carcinoma cells were infrequent. However, in all cases, sputum cytology was correctly interpreted because squamous differentiation was easily recognized.
Adenocarcinoma↗
Immunocytochemical diagnosis of small cell undifferentiated carcinoma of the cervix.
Ethanol-fixed and Papanicolaou-stained smears of 5 cases of cervical small cell undifferentiated carcinoma and 10 control cases of non-small cell cervical cancer were immunocytochemically examined with monoclonal antibodies (MAbs) against cluster 1 small cell lung cancer (SCLC) antigen, which were found to react with neural cell adhesion molecules (N-CAM). MAbs against cluster 1 SCLC antigen used in this study were NCC-LU-243, NCC-LU-246 and anti-Leu-19. The expression of cluster 1 SCLC antigen was recognized by MAb NCC-LU-243 and NCC-LU-246 in all five cases and by anti-Leu-19 MAb in three. The cluster 1 SCLC antigen was not detected in any of the 10 non-small cell cervical cancers. These results suggest that cluster 1 SCLC antigen is stable and immunocytochemically detectable in Papanicolaou-stained smears and is helpful in the cytologic diagnosis of cervical small cell undifferentiated carcinoma.
Adenocarcinoma↗