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Biomedical subjects

Y Tsuruha

Publications and source records attributed to Y Tsuruha.

9 recordsLinked to original sources

Multicenter studies of 2% nitroglycerin ointment in patients with heart failure.

Nitroglycerin ointment (NTGO) was applied to the precordial area in 88 patients with heart failure arising from acute myocardial infarction (AMI) or other types of heart disease, and its effects on hemodynamic parameters were determined. After NTGO was applied, patients' systolic blood pressure (P less than 0.001), double product (heart rate X systolic pressure, P less than 0.001), pulmonary capillary wedge pressure (P less than 0.001), and systemic vascular resistance (P less than 0.001) decreased significantly. These changes began 30 to 60 minutes after NTGO was applied and lasted two to six hours. Based on these hemodynamic changes, we conclude that NTGO is beneficial for patients with heart failure due to AMI or other heart disease.

Administration, Topical↗

Counter measures against death from arrhythmias in acute myocardial infarction: mortality of the disease in a hospital at different periods with changing care systems. Factors of delay in the pre-hospital phase.

The results of treatment of 400 patients with established acute myocardial infarction in a hospital at different periods with changing care systems are described. Significant reduction of death from arrhythmias could be obtained only when an organization with immediate availability of well-trained medical personnel and reliable actual continuous monitoring of electrocardiograms had been established. Components of delay in the pre-hospital phase of acute myocardial infarction were also studied. There were two significant factors in delay: one was delay due to ignorance of patients about the disease, second was the delay after consultation of family doctors until arrival at the CCU. Time is consumed in the latter factor mainly in making of definite diagnosis. The implication of these data in the management of patients with a diagnosis of acute myocardial infarction are discussed.

Arrhythmias, Cardiac↗

Unusual mechanism in the initiation of the paroxysmal supraventricular tachycardia in a patient with WPW syndrome.

A heretofore unreported unusual mechanism in the initiation of the paroxysmal supraventricular tachycardia (PSVT) in a patient with WPW (Wolff-Parkinson-White) syndrome was observed using His bundle recordings. The patient initially had some degree of AV conduction disturbance at the level of the AV node. A premature atrial impulse initially activated the ventricle exclusively through the accessory pathway and the same impulse re-excited the ventricle via the AV nodal-His axis after finishing the pure pre-excitation with marked prolongation of the AH and the HV intervals. After finishing this double ventricular response it traversed to the atrium to produce the PSVT.

Atrioventricular Node↗

Brady-Memo.

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Bradycardia↗