[Clinical evaluation of Konsul cortisol RIA kit as a method of serum cortisol estimation. (author's transl)].
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Adrenal Gland Diseases↗
Biomedical subjects
Y Toya
Publications and source records attributed to Y Toya.
Characteristic localization of alpha 1- and alpha 2-adrenoceptors in the human kidney.
1. The localization of alpha-adrenoceptors in the plasma membranes of human kidney were investigated by radioligand binding, using an alpha 1-antagonist, [3H]-bunazosin, and an alpha 2-antagonist, [3H]-rauwolscine. 2. Both the maximum binding (Bmax) and dissociation constant (Kd) of [3H]-bunazosin were greater in the cortex than in the medulla. The Bmax of [3H]-rauwolscine in the medulla was greater than in the cortex. 3. Thus, alpha 1-adrenoceptors appeared to be localized predominantly in the cortex, while the alpha 2-adrenoceptors were mainly present in the medulla of the human kidney.
Adrenergic alpha-Antagonists↗