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Biomedical subjects

Y Tano

Publications and source records attributed to Y Tano.

At least 235 records · Page 13Linked to original sources
PubMed1979

Streaks (schlieren) as a sign of rhegmatogenous detachment in vitreous surgery.

Schlieren or streaks can be observed as light passes through incompletely mixed fluids having different refractive indices. During vitreous surgery, the vitreous humor is replaced by an aqueous solution whose density and refractive index differ from those of subretinal fluid. The observation of schlieren during vitrectomy therefore suggests the presence of subretinal fluid and a retinal hole. After observing this sign, a careful search should be made for the retinal break if it has not been previously diagnosed.

Body Fluids↗
PubMed1979

Treatment of intraocular proliferations with intravitreal steroids.

Autotransplantation of 250,000 tissue cultured fibroblasts from rabbit rump skin into the vitreous cavity results in intravitreal strand formation and traction retinal detachment (27 of 47 eyes, 57%). A single intravitreal injection of 1 mg of dexamethasone alcohol inhibits fibroblast growth as judged by the significantly reduced number of retinal detachments (11 of 46 eyes, 24%).

Animals↗
PubMedDate not supplied

Gas stress test for assessment of corneal endothelial function.

PURPOSE: This study was undertaken to evaluate the endothelial pump function by monitoring both corneal swelling response under hypoxia and dehydration response following hypoxia in vivo. METHODS: Humidified nitrogen gas was used to obtain corneal swelling, and humidified gas mixed with oxygen and nitrogen was used for corneal dehydration. First, in 6 young volunteers, we investigated the most suitable oxygen level for evaluating pump function by changing oxygen levels. Then, with the optimal oxygen level, we attempted to evaluate pump function in 53 normal subjects, 5 Fuchs' dystrophy patients, and 3 iridocorneal endothelial syndrome (ICE) patients. RESULTS: Swelling rate showed similar values regardless of age, but both dehydration rate and swelling rate plus dehydration rate decreased with aging. The swelling rate of 5 guttata corneas was significantly higher than that of age-matched control corneas. In contrast, dehydration rate markedly decreased in guttata corneas, while the swelling rate plus dehydration rate of guttata corneas was comparable to that of age-matched corneas. In the 3 ICE corneas, however, swelling rate, dehydration rate, and swelling rate plus dehydration rate were markedly lower than those of both the fellow corneas and the age-matched control corneas. CONCLUSION: These observations lead us to conclude that in order to evaluate pump function, it is necessary to monitor not only dehydration response following hypoxia but also swelling response under hypoxia.

Adult↗
PubMedDate not supplied

Multicenter retrospective study of retinal detachment associated with atopic dermatitis.

PURPOSE: Epidemiological and clinical study of retinal detachment associated with atopic dermatitis. METHODS: A multicenter retrospective study. RESULTS: We analyzed the records of 417 eyes of 348 patients operated on during 5 years from 1989 to 1993 and followed up for more than 6 months by vitreo-retinal specialists in 33 hospitals throughout Japan. The number of eyes operated on increased yearly from 42 in 1989 to 132 in 1993. These cases associated with atopic dermatitis were 2.3% of the average number of eyes operated on for rhegmatogenous retinal detachment during the same period, but when restricted to the Kanto area or further to Tokyo only, the percentage was as high as 3.8% and 4.7%, respectively. CONCLUSION: Clinical characteristics of retinal detachment previously reported, such as traumatic slapping or rubbing of the lids by patients as the most likely pathogenetic factor, and high incidence of cataract and proliferative vitreoretinopathy, were confirmed. The primary surgical procedure was scleral buckling in 78% of the cases and vitreous surgery in 22%, and initial and final reattachment rates were 75.3% and 92.6%, respectively.

Adolescent↗
PubMedDate not supplied

Emulsification tendency of silicone-phenylsilicone copolymer.

PURPOSE: We compared the emulsification tendency of silicone-phenylsilicone copolymer (DPC; 5%-phenylated, specific gravity 0.984) with that of silicone oil (SO; specific gravity 0.966) and fluorosilicone oil (FSO; specific gravity 1.256), all of which are used clinically as intraocular tamponades. METHODS: We investigated the tendencies of emulsification in SO, FSO, and DPC. Each was placed in a separate glass container with equal amounts of albumin solution (1 mg/mL) or 1 gamma-globulin solution (1 mg/mL) and shaken. We also investigated the toxicity of DPC in the rabbit eye. Following vitrectomy, we injected DPC into the vitreous cavity and assessed the retinal damage histologically. RESULTS: The SO and DPC, because their specific gravities, are closer to water, tended to become less emulsified than did FSO. We found that DPC did not cause any severe histological damage in the rabbit retina. CONCLUSION: Highly phenylated DPC is slightly heavier than water and may be used instead of FSO to treat inferior retinal detachment.

Animals↗