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Biomedical subjects

Y Tanahashi

Publications and source records attributed to Y Tanahashi.

At least 73 records · Page 4Linked to original sources
PubMed1981

The effect of estramustine phosphate on prostatic cancer estimated by transrectal ultrasonotomography.

Transrectal ultrasonotomography was performed in 44 patients with prostatic cancer before, during, and after estramustine phosphate (Estracyt) administration. In 75.7% of 37 previously untreated patients, the deformity of the horizontal section of the prostate with prostatic cancer was corrected considerably, while in 89.2%, prostatic weight was remarkably reduced. In 57.1% of seven previously treated patients, appreciable changes were also observed in the shape and weight of the prostate. We concluded that estramustine phosphate was effective not only for untreated prostatic cancer, but also, at least in some degree, for relapsed cases.

Aged↗
PubMed1980

Clinical evaluation of inside echo patterns in gray scale prostatic echography.

Improved gray scale echograms in transrectal ultrasonography clearly can visualize the anatomical structure of and pathological changes in the prostatic gland. This study includes the classification of ultrasonic findings from the prostatic gland into acoustical pattern groups--solid, cystic and mixed--as well as into pathological-anatomical pattern groups--internal gland, external gland, nodule, stone and miscellaneous. The diagnostic accuracy of prostatic diseases using pattern analysis of prostatic inside echoes was 89 per cent, a 9 per cent improvement over that provided by conventional display.

Calculi↗
PubMed1979

Gray scale transrectal ultransonography of the prostate.

Gray scale transrectal ultrasongraphy provides refined visualization of the texture of the prostate and other intrapelvic organs. Diagnostic accuracy of the transrectal scan has been successfully registered at 91% in benign prostatic hyperplasia, 85% in cancer, 89% in prostatitis, and 88% in total prostatic scans. Furthermore, prostatic calculi were visible in the tomograms of both normal and abnormal prostates at a higher frequency than generally considered. Other applications of ultrasonic control, such as during transurethral resection or cryosurgery of the prostate and staging of bladder tumors, are profitable using the gray scale technique.

Calculi↗
PubMed1979

Effect of the autonomic blockade on the automaticity of the A-V junctional pacemaker in awake dogs.

The effect of the autonomic blockade on the automaticity of the A-V junctional pacemaker was evaluated in 15 awake dogs with experimentally induced A-V junctional rhythm. The duration of asystole after overdrive (D.A.O.) in these dogs was prolonged significantly in accordance with increase in the drive rate, and the mean +/- SD of the D.A.O. reached 4.7 +/- 1.1 seconds (N = 15) after overdrive at 2.5 times the spontaneous heart rate. After administration of atropine (0.4 mg/kg; i.v.) to eight dogs, the mean +/- SD of the D.A.O. at the same rate decreased from 4.5 +/- 0.9 to 3.4 +/- 1.2 seconds. After administration of practolol (0.5 mg/kg; i.v.) to the seven other dogs, the mean +/- SD of the D.A.O. at the same rate increased remarkably from 4.9 +/- 1.3 to 9.4 +/- 3.0 seconds. Intravenous injection of practolol (0.5 mg/kg) had no effect upon the D.A.O. in the five dogs with sinus rhythm. Thus, it is suggested that (1) the sympathetic nerve might play a more important role in regulating the automaticity of the A-V junctional pacemaker than the vagus and (2) it physiologically might take over 5.0 seconds for the A-V junctional pacemaker to initiate an escape beat during longstanding sinus arrest, if a marked dysfunction of the A-V junctional pacemaker occurs due to a decrease in tension of the sympathetic nerve.

Animals↗
PubMed1977

Staging of bladder tumors by means of transrectal ultrasonography.

Transrectal ultrasonography is a specially devised technique to obtain clear tomograms of the intrapelvic organs, such as the prostate, urinary bladder and seminal vesicles. We used this technique to evaluate 64 patients with bladder tumors. The results were compared with histological findings after exploratory surgery. Ultrasonograms of these tumors were estimated on the basis of bladder wall irregularity, bladder deformity, bladder capacity and extravesical spread of tumor. Each tumor stage showed characteristic ultrasonic features. Extravesical spread of tumor, which was observed in 67 percent of stage D tumors, proved to be an important finding to distinguish stage D tumours from other tumor stages. We suggest these features as diagnostic criteria for ultrasonic staging of bladder tumors.

Humans↗
PubMed1977

Mass screening program for prostatic diseases with transrectal ultrasonotomography.

A special chair-type apparatus for transrectal ultrasonotomography was developed in our laboratory 3 years ago. We did a mass screening program for prostatic disease, using this equipment as the primary study in the system. The 132 apparently normal men evaluated ranged in age from 40 to 76 years (mean 55.0). The 48 patients suspected of having prostatic disease underwent secondary studies, consisting of the usual urological examinations. Prostatic disease was detected in 24 cases, including 18 cases of benign prostatic hyperplasia. Thus, the model program revealed an extraordinarily high prevalence of latent prostatic disease among apparently normal older men.

Adult↗
PubMed1977

[An experimental study on canine A-V junctional pacemaker--evaluation of the automaticity by overdrive suppression and autonomic blockade by practolol and atropine].

1. The automaticity of the A-V junction was evaluated in 15 awake dogs with experimentally induced A-V junctional rhythm. 2. The spontaneous heart rate of these dogs ranged from 54 to 112 beats a minute, showing about 1.5-2.5 times slower than that of control dogs with sinus rhythm. The duration of asystole after overdrive in these dogs prolonged significantly in accordance with an increase in the frequency of stimulation for overdrive, and its mean +/- SD attained 4.7 +/- 1.1 seconds after overdrive at a rate of 2.5 times the spontaneous heart rate. 3. By administration of atropine (0.04 mg/kg, i.v.) to 8 dogs, the duration of asystole after overdrive, at a rate of 1.5 times the spontaneous heart rate, decreased from 2.6 +/- 0.8 to 1.5 +/- 0.4 seconds. By administration of practolol (0.5 mg/kg, i.v.) to 7 other dogs, the duration of asystole after overdrive increased from 3.0 +/- 1.1 to 6.4 +/- 2.2 seconds. 4. It should be suggested that, (1) about 5 seconds of asystole might physiologically occur before the initiation of the A-V junctional escape beat during the long-standing sinus arrest, and (2) the sympathetic nerve might play a more important role in regulating the automaticity of the A-V junction than the vagus nerve.

Animals↗