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Biomedical subjects

Y Takeno

Publications and source records attributed to Y Takeno.

At least 19 recordsLinked to original sources

Variation in appearance of glioma on serial thallium-201 single photon emission computed tomography--case report.

A 63-year-old female presented with recurrent glioblastoma at the site of a right parietal glioblastoma which was diagnosed 1 year before. She was treated at that time by total removal of the tumor, irradiation, and chemotherapy. Four months after the initial treatment, serial thallium-201 single photon emission computed tomography (201Tl SPECT) showed increased uptake at the edge of the original tumor site. The index, the ratio of 201Tl uptake in the lesion to the normal brain, was 2.9 which suggested a recurrent tumor. Magnetic resonance images with gadolinium over the next 7 months demonstrated an enhanced mass lesion at the site of primary tumor resection and a new enhanced mass in the right temporal lobe. The lesion in the right parietal lobe had a 201Tl uptake index of 2.5, while the lesion in the right temporal lobe had an index of 1.5. Re-craniotomy and total resection of the tumors in the right parietal and temporal lobes were performed. The histological diagnosis of both tumors was glioblastoma. The proposed use of 201Tl SPECT for the differential diagnosis of recurrent glioma and radiation necrosis should be carefully considered because the 201Tl uptake index can vary in tumor with the same malignancy grade.

Brain Neoplasms

Medullary venous malformation with an arterial component associated with a ruptured aneurysm--case report.

We report the rare of occurrence of a medullary venous malformation (MVM) with an arterial component associated with a saccular aneurysm on the opposite side. This 49-year-old male patient was admitted with headache and vomiting. He was diagnosed as having a subarachnoid hemorrhage on the basis of bloody cerebrospinal fluid. Angiography revealed a saccular aneurysm at the junction of the internal carotid and posterior communicating arteries on the left side. A MVM with an arterial component was also seen in the right basal frontal lobe. On the seventh hospital day, the aneurysm was clipped via a left frontotemporal craniotomy. The postoperative course was uneventful. There are many hypotheses concerning cerebral aneurysms; some are thought to derive from persistent primitive arteries in the early fetal period. On the other hand, MVM is thought to be intimately related to arteriovenous malformation, which is believed to develop from the premordial vascular plexus, also in early fetal life.

Brain Neoplasms

[Evaluation of bone atrophy by microdensitometry and effect of active vitamin D3 (1 alpha-OH-D3) administration in patients receiving anticonvulsants].

Attention has been paid to bone atrophy caused by oral anticonvulsants. Bone atrophy has been judged on X-ray picture in combination with measuring bio-chemical parameters such as serum calcium (Ca), phosphorus (P) and alkaline phosphatase (Alp), and assessing X-ray findings such as bone density and morphological findings of bone. However, the conventional techniques based on these parameters and findings do not always permit diagnosing the disease. Microdensitometric (MD) method, recently developed by Inoue et al. as a method to assess the grades of severity of bone atrophy on X-ray picture of the metacarpal bone II, has been improved in its exactitude and widely applied in clinical practice for diagnosis of bone atrophy. In 174 patients receiving anticonvulsants, the severity of bone atrophy was quantitatively assessed by the MD method. 1 microgram/day of active vitamin D3 (1 alpha-OH-D3) was administered to patients presenting abnormal MD findings indicative of bone atrophy, and the results were as follows: 1. Bone atrophy of grades initial to III was noted in 46 patients (26.4%). There was no sex-difference in incidence of bone atrophy. 2. In patients receiving valproic acid (VPA) for two years or longer, there was no correlation between the duration of VPA treatment and the severity of the disease as assessed by MD method or its incidence, nor between the mean blood level of VPA and the severity. 3. Bone atrophy was found in 25 (29.1%) of the patients receiving anticonvulsants even for less then two years. Five of these 25 patients were alcoholism , and 9 patients received steroids.(ABSTRACT TRUNCATED AT 250 WORDS)

Absorptiometry, Photon

Epidemiology of spontaneous pneumothorax in women.

An epidemiologic study was done on spontaneous pneumothorax in women. Six hundred sixty-four patients with spontaneous pneumothorax comprising 409 with idiopathic pneumothorax (61.6 percent), and 255 with secondary pneumothorax (38.4 percent) were studied. By age, idiopathic pneumothorax had its peak incidence in the 20s and secondary pneumothorax the 30s. Secondary pneumothorax included iatrogenic pneumothorax resulting from acupuncture treatment. The female patients were not so thin and tall as the male patients. The percentage of positive family history among the female patients was 4.42 percent in the idiopathic type and 0.45 percent in the secondary type. The percentage in the male idiopathic type of pneumothorax was 2.29 percent. Catamenial pneumothorax and pneumothorax with pulmonary hamartoangiomyomatosis are well known as specific in female subjects, but the cases are rare. Nonetheless, attention should be paid to female-specific rare types, for the etiology of idiopathic pneumothorax.

Adolescent

Physical constitution and smoking habits of patients with idiopathic spontaneous pneumothorax.

This is a report on a statistical study comparing the Kaup index and the level of tobacco consumption of patients with idiopathic spontaneous pneumothorax and those of healthy subjects. A statistically significant difference was found between the average Kaup index of the patients with idiopathic spontaneous pneumothorax and that of normal healthy individuals in Japan as published by the Ministry of Health and Welfare. A statistically significant difference was also found in the physical features between 2,433 males with idiopathic pneumothorax and 1,906 healthy males when compared by means of the Kaup index. Again, a statistically significant difference was noted in the level of tobacco consumption between the males with idiopathic pneumothorax and normal males when compared by means of the Brinkmann index. The Kaup index of idiopathic pneumothorax patients was lower than that of healthy subjects, while the level of tobacco consumption of the former was higher. Idiopathic spontaneous pneumothorax is related to thin and tall individuals and the level of tobacco consumption among such patients is higher than among healthy subjects.

Adolescent

[Pneumothorax].

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Humans