Search PubMed⌕ Search

Biomedical subjects

Y Seto

Publications and source records attributed to Y Seto.

204 records · Page 12Linked to original sources
PubMedDate not supplied

Vascular invasion of early gastric cancer at resection line.

Vascular invasion is observed in early gastric cancers (EGCs) as well as advanced gastric cancers. However, there have been no studies assessing adequate surgical margins for EGCs with reference to vascular invasion. A total of 452 EGCs were retrospectively evaluated. Vascular invasion, via lymphatics and/or venous vessels, was examined histologically. The distance from the tumor edge to infiltration was measured when cancer cells extended beyond the tumor through vessels. Vascular invasion was histologically confirmed in 41 EGCs (9.1%). Invasion was in one-fourth (40/166, 24.1%) of submucosal cancers, but in only one (1/286, 0.3%) mucosal cancer. Five EGCs (1.1%) showed infiltration beyond the tumor through the vessels and the maximum distance from the tumor edge to the most distal site of infiltration was 4 mm. In conclusion, a 2 cm surgical margin, as recommended in Japanese surgical textbooks, is adequate for EGCs with reference to vascular invasion.

Humans↗
PubMedDate not supplied

Arthroscopy for slipped capital femoral epiphysis.

Arthroscopy was performed in five hips with slipped capital femoral epiphysis (SCFE) before pinning in situ. Arthroscopy disclosed erosion of acetabular cartilage in the anterosuperior region and damage to the posterolateral aspect of the acetabular labrum. Cartilaginous erosion and transverse cleft were identified on the anterior surface of the femoral head. These findings support the hypothesis that all pathomechanisms of SCFE are caused by traumatic factors. Arthroscopy for SCFE is also clinically useful in reducing hip pain. Arthroscopy performed simultaneously with pinning in situ can permit early exercise of the joint.

Adolescent↗
PubMedDate not supplied

Intra-operative diagnosis of N2 lymph node metastasis of gastric cancer.

BACKGROUND/AIMS: Limited lymph node dissection for gastric cancer, which is prevalent in Western countries, leaves cancer cells in the second tier of nodes in patients who have metastasis in those nodes. It is, however, difficult to correctly diagnose nodal status during surgery. The present study was, therefore, designed to examine how to detect N2 metastasis intra-operatively. METHODOLOGY: Five hundred and eight patients undergoing extended lymph node dissections for gastric cancer were retrospectively analyzed. Accuracy of the intraoperative diagnosis of node involvement based on macroscopic findings was investigated, according to the N stage and histological type of the tumor. Furthermore, the distributions of N2 metastasis were clarified, according to tumor site. RESULTS: Intra-operative macroscopic findings were frequently assessed as being less severe than histological findings in cases with N2 metastasis (61.9%, 39/63). Intra-operative recognition of N2 metastasis was significantly lower in the cases with undifferentiated adenocarcinoma (28.2%, 11/39) than in those with differentiated adenocarcinoma (56.5%, 13/23). The distributions of N2 metastasis revealed nodes along the left gastric and common hepatic arteries to be the key junctions for lymphatic flow from the middle and lower thirds of the stomach, respectively. CONCLUSIONS: Intra-operative diagnosis of N2 metastasis is difficult to make based on macroscopic findings, especially in undifferentiated tumors. To detect N2 metastasis intra-operatively, the nodes along the left gastric or common hepatic artery should be submitted to frozen section examination for primary tumors located in the middle or lower third of the stomach, respectively.

Adenocarcinoma↗
PubMedDate not supplied

Results of extended lymph node dissection for gastric cancer cases with N2 lymph node metastasis.

The therapeutic value of extended lymph node dissection (D2) for gastric cancer remains controversial. Limited lymph node dissection, however, leaves cancer cells in the second tier of nodes (N2) in patients with N2 metastasis. This retrospective study was, therefore, undertaken to clarify which patients would be most likely to benefit from D2 dissection, even with N2 metastasis. Two groups, N2 cases with (n = 40) and without (n = 24) the development of recurrence after curative surgery, were compared. Borrmann type IV and serosal invasion were significantly related to recurrence. The number of metastatic nodes did not differ significantly between the two groups. All (7/7) of the Borrmann type IV cases with N2 metastasis developed recurrence and died. However, one quarter (7/30) of the cases with serosal invasion and N2 metastasis showed no sign of recurrence. D2 dissection is a surgical treatment which offers the potential to cure gastric cancers, other than Borrmann type IV tumor, with N2 metastasis.

Female↗
PubMedDate not supplied

Location of the femoral head in developmental dysplasia of the hip: three-dimensional evaluation by means of magnetic resonance image.

By using magnetic resonance imaging, we analyzed the position of the femoral head in 21 hips of 21 infants with developmental dislocation. The femoral head changed its location according to the hip position. In type A dislocation, the head was anterior to the acetabulum when the hip was extended, and it was posterior when the hip was flexed. There was wide contact area between the femoral head and the acetabulum in any hip position. In type B, the head was on the rim of the acetabulum when the hip was extended. When the hip was flexed, the head was on the posterior rim of the acetabulum, and there was no contact between the femoral head and acetabular cartilage. Some heads slipped into the socket with a click phenomenon when the hip was flexed/abducted. In type C dislocation, the head was on the edge of the acetabulum when the hip was extended. When the hip was flexed, the head moved posteriorly, and it was completely out of the socket.

Acetabulum↗