Search PubMed⌕ Search

Biomedical subjects

Y Seki

Publications and source records attributed to Y Seki.

At least 253 records · Page 14Linked to original sources
PubMed1979

Catalytic activity of the chromophore of desulfoviridin, sirohydrochlorin, in sulfite reduction in the presence of iron.

Sirohydrochlorin chromophore prepared by acetone/HCl treatment of desulfoviridin, the sulfite reductase from Desulfovibrio, catalyzed the reduction of sulfite to sulfide and thiosulfate in equimolar amounts when coupled with a hydrogen-hydrogenase-methyl viologen system. This activity was manifested at acidic pH and increased exponentially with decrease in pH. The Km value for sulfite was nearly 10 times that of desulfoviridin. Inorganic iron was necessary for the reduction, since inactivation occurred on passage through a Sephadex LH-20 column or in the presence of 2,2'-bipyridine, and reactivation was observed on adding iron. The chromophore catalyzed the reduction of dithionite and hyroxylamine.

Desulfovibrio↗
PubMed1975

Carcinoma of the cystic duct: case report.

A case of carcinoma of the cystic duct is presented and comprehensive review of the literature was provided. Since no characteristic clinical signs are present, the diagnosis can only be made incidentally at the time of laparotomy for non-visualizing gallbladder. Even then histological study of the resected specimen is mandatory. In our present case after the confirmation of the diagnosis the second look exploration was done. However, careful examination of the bile duct system failed to find evidence of carcinomatous involvement suggesting that carcinoma found in the cystic duct was of a primary and not a secondary invasion. The present case constitutes the nineteenth case which meets completely the criteria proposed by Farrar. Since the only hope or cure lies with the early diagnosis of the disease, early exploratory laparotomy and prophylactic removal of nonfunctioning or calculous gallbladder are recommended.

Adenocarcinoma, Papillary↗