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Biomedical subjects

Y Saudan

Publications and source records attributed to Y Saudan.

At least 37 records · Page 2Linked to original sources
PubMed1983

[Acute myelo-monocytic leukemia with collagenous medullary fibrosis and osteosclerotic lesions].

A case of acute myelo-monocytic leukemia (M4) in a 75 year old man with multiple osteosclerotic lesions is reported. Bone metastases were clinically and radiologically suspected. A surgical bone marrow biopsy at the iliac crest revealed a massive infiltrate of blasts with medullary fibrosis, large areas of osteosclerosis and foci of necrosis. Osteosclerosis is rarely observed during acute leukemias in adults. Differential diagnosis with acute myelofibrosis is discussed.

Aged↗
PubMed1982

[Monoarthritis caused by Mycobacterium intracellulare. Personal observation of 2 cases and review of the literature].

The authors report two cases of arthritis of a proximal interphalangeal articulation due to Mycobacterium (M) intracellulare. In both cases, an intra-articular corticosteroid injection, given for preexisting pain, was responsible for infection. Both diagnoses were based on results from cultures of biopsied tissue. Histological findings in one of the cases were non-specific, whereas tuberculoid granulomas were present in the other. Articular destruction had occurred in both patients at the time of diagnosis. M. intracellulare was sensitive to ethambutol in the first case, and to ethambutol and cycloserine in the second. The evolution of the disease could not be ascertained in one patient lost to follow-up. The second patient's course of disease was favorable after surgical excision and 10 months of tuberculostatic drugs. The study reviews the principal contributions of the literature.

Adult↗
PubMed1979

[Sacroiliac changes, HLA-B27 negative, in primary hyperparathyroidism and osteomalacia].

Radiological sacroiliac (SI) changes were found in 3 patients, 2 with primary hyperparathyroidism (1 also with associated chondrocalcinosis) and 1 with osteomalacia. Osteomalacia was due to celiac disease. None of the 3 patients, all females, had a history of psoriasis, urethritis, iritis or chronic colitis. There was no renal function impairment. Peripheral joints were affected in the patient with associated condrocalcinosis. HLA B 27 was negative in all cases. Low back pain and vertebral stiffness were present in the patient with osteomalacia. A dramatic improvement in pain and stiffness ensued after vitamin D injections. These SI lesions, which may simulate ankylosing spondylitis, were attributable to subchondral bone changes related to the metabolic bone diseases. In the case of osteomalacia the SI lesions were predominantly on the right side, where there was a Looser's zone on the ischial ramus suggesting that pseudofractures could be a cause of SI changes. Metabolic osseous diseases such as osteomalacia or primary hyperparathyroidism should be investigated in cases of HLA B 27 negative radiological "sacroiliitis".

Aged↗
PubMed1978

[Auricular fibrillation and acute aortic insufficienncy in Reiter's syndrome].

The case is presented of a 27-year old male with typical Reiter's sundrome (RS) and cardiac lesions. Eight months after the initial onset of the joint and mucosal symptoms, atrial fibrillation and signs of cardiac failure suddenly supervened. Rheumatic fever, hyperthyroidism and myocardial infarction were ruled out. Digitalization and Valsalva maneuvers produced a return to normal sinus rhythm. At the same time a diastolic murmur was heard and the diastolic pressure fell to 40 mm Hg, suggesting acute aortic insufficiency. This carditis was attributed to RS. The evolution was favourable, although a mild degree of aortic insufficiency persisted.

Adult↗
PubMed1978

[X-ray examination of the sterno-manubrial joint in ankylosing spondylitis and Reiter's disease (author's transl)].

In 19 patients with ankylosing spondylitis, 11 presented some lesions of the manubrio-sternal joint. In 3 cases these lesions were more advanced than the sacro-iliac alterations which were very slight or even doubtful. In 8 patients with severe Reiter's disease, 7 developed an ankylosing spondylitis and 2 presented involvement of the manubrio-sternal joint 8 weeks, respectively 10 weeks after the appearance of the first symptoms.

Adult↗
PubMed1978

Talalgia. A review of 30 severe cases.

Seronegative spondyloarthritides (Reiter's syndrome, ankylosing spondylitis, or psoriatic arthritis) was diagnosed in 24 of 30 patients with severe heel pain. Most of the patients were carriers of the antigen HLA B27. Talalgia was frequently the first symptom of disease. Heel surgery is contra-indicated during the inflammation phase, since it may cause local aggravation and risk of ankylosis of the talocalcaneal articulation. Other causes of heel pain include tendon chondrocalcinosis, local tuberculous infection, and nodular tendinitis caused by a partial rupture of the tendon. On the other hand, severe talagia was rarely found in rheumatoid arthritis, and no case was related to the presence of tophi or xanthomas of the Achilles tendon.

Achilles Tendon↗