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Biomedical subjects

Y S Cho

Publications and source records attributed to Y S Cho.

105 records · Page 6Linked to original sources

Arterial thrombosis associated with nephrotic syndrome--a case report and review (adult cases in the English literature).

The thromboembolic complications of nephrotic syndrome are reasonably common, including spontaneous peripheral venous and/or arterial, pulmonary arterial, and renal venous occlusions. However, in comparison to the relatively high incidence of the venous thromboembolic complications with hypercoagulable status, arterial thromboses have been reported much less and it was only 20 cases in the English literature so far. Furthermore, the most cases were pediatric patients rather than adults. Therefore, this report describes an adult nephrotic cases complicated by superior mesenteric artery thrombosis leading to death via catastrophic hospital course. Also, we reviewed the literature in English regarding cases of arterial thromboses in adult nephrotic patients with special interest to locations of thrombosis, underlying histopathologic types of glomerulopathy, and use of steroids or diuretics before its development.

Humans↗

Dietary casein and soybean protein affect the concentrations of serum cholesterol, triglyceride and free amino acids in rats.

This work was undertaken to investigate the concentrations of free amino acids in blood after food was withheld from growing, male Wistar rats fed cholesterol-free, low fat (1 g corn oil/100 g) diets with casein or soybean protein for 2 wk. A diet containing 22.5 or 23.5 g/100 g of soybean protein was hypocholesterolemic compared with a diet containing 20.0 g casein/100 g diet. A comparison of serum amino acids in soybean protein-fed vs. casein-fed rats showed that, whereas concentrations of many amino acids were lower in the soybean protein-fed rats compared with the casein-fed groups, glycine was the only amino acid having a higher concentration. Further, alanine was significantly lower in the soybean protein-fed rats compared with the casein-fed rats, and the protein-induced differences in glycine and alanine concentrations of unfed rats were reproducible. When diets containing 15.0% casein or 30.0% soybean protein, a casein diet supplemented with glycine and a soybean protein diet supplemented with methionine were compared, the changes in serum glycine and alanine correlated with the changes in serum cholesterol. Concentrations of several amino acids, particularly valine, leucine and tyrosine, also changed when serum cholesterol concentrations varied, but these effects could not be explained by our experiments. The results suggest that a change in serum concentration of glycine and alanine of unfed rats may be related to the change in serum cholesterol concentration.

Alanine↗

Significant changes of bronchial responsiveness to methacholine after early asthmatic reaction to toluene diisocyanate (TDI) in a TDI-sensitive asthmatic worker.

Current asthma is often diagnostically excluded by the presence of normal bronchial responsiveness. We report on a TDI-induced occupational asthma patient with normal bronchial responsiveness. He had suffered from shortness of breath during and after TDI exposure for several months. His initial methacholine bronchial challenge test showed a negative response. The bronchoprovacation test with TDI showed an isolated immediate bronchoconstriction. The following methacholine bronchial challenge tests revealed that the bronchial hyperresponsiveness developed seven hours after the TDI challenge (methacholine PC20:5.1 mg/ml), progressed up until 24 hours, and returned to normal on the seventh day. This case provides evidence that the response of the airway to TDI may not always be accompanied by bronchial hyperresponsiveness to methacholine. Screening programs utilizing methacholine challenges may not always identify TDI-sensitized asthmatic workers.

Adult↗

[Mental conflict of urban Korean housewives--a qualitative analysis of 20 interviews].

This study analysed marital conflicts, related factors, and adjustments to those conflicts described by urban Korean women. The purpose was to discover directions for resolutions that would enhance the helpfulness of volunteers or professionals working with women in counselling settings. The investigator interviewed 20 married women, all mothers and housewives living in Seoul, attending marriage encounter programs and the Lifeline telephone counselling service. An interview schedule using six open-ended questions guided the data collection which took place between May 31 and December 29, 1988. Content analysis of the data revealed, in order of reported frequency, the following areas of conflict: relationships between husband wife, relationships with children, relationships between the wife and her mother-in-Law, unsatisfied sexual needs, the husband's extra marital relationships, lack of self actualization and financial matters. Analysis of the data suggested the following factors were related to the conflicts: reasons for marriage, traditional views about marriage and divorce including to accept a marriage arranged by the parents, the husband's traditional attitude toward the sex role of the wife, the husband's patriarchal authoritarianism, and his attitude toward the wife's employment outside the home. The women thought these conflicts severely affected their relationships within the family, particularly with their children. Literature suggests links with such poor parent-child-family relationships and adolescent or young people's social problems. Volunteers or professionals working with married women in counselling situations need to be conscious of the possibility of these conflicts during assessment, and direct their guidance toward such conflict resolution. The researcher makes several suggestions which include the need for the husband to give emotional support to his wife, to recognize the worth of housework, to share the work of the home, to find ways to enhance the wife's self-actualization and to ease dreary housework routines by providing modern appliances.

Conflict, Psychological↗

[Cadmium toxicity on rat's placenta: effect of zinc].

Maternal administration of CdCl2 (40 microM/kg) on the 19th day of gestation produces several ultrastructural modifications of the rat placental barrier which may be held responsible for fetal death. ZnCl2 (100 microM/kg) administered simultaneously with cadmium antagonises the cadmium toxicity in syncytial layer I.

Animals↗

Congenital lacrimal system obstruction: treatment with balloon dilation.

PURPOSE: To evaluate the safety and effectiveness of balloon dilation for the treatment of congenital lacrimal system obstruction. MATERIALS AND METHODS: Fluoroscopically guided balloon dilation was attempted in 20 eyes of 16 patients with an age range of 12-78 months (mean, 33 mo) for congenital lacrimal system obstruction. Fifteen eyes had complete obstruction at the valve of Hasner, three eyes had completely obstruction at the junction between the lacrimal sac and the nasolacrimal duct, and two eyes had partial obstruction at the nasolacrimal duct. Under general anesthesia, a ball-tipped guide wire was introduced through the superior punctum into the inferior meatus of the nasal cavity and pulled out through the naris with use of a hook. A deflated 3-mm-diameter balloon catheter was then advanced in a retrograde direction and the balloon was dilated. Every patient underwent an ophthalmic evaluation before the procedure and was scheduled to be followed with office examination at 1, 3, and 6 months after the procedure. RESULTS: There were no major complications. "Technical success" was defined as free passage of contrast medium through the entire lacrimal system to the nasal cavity. The procedure failed in one eye. After balloon dilation, all 19 eyes in which technical success was achieved showed improvement of epiphora. During the follow-up period of 2-33 months (mean, 16 mo), all eyes maintained improvement of epiphora and needed no further treatment. CONCLUSION: Balloon dilation is a safe and effective therapeutic technique for the treatment of congenital lacrimal system obstruction.

Catheterization↗

Recovery of nasal physiology after functional endoscopic sinus surgery: olfaction and mucociliary transport.

We assessed the changes in olfaction and mucociliary transport after functional endoscopic sinus surgery (FESS) in 80 patients with chronic paranasal sinusitis. Olfaction was evaluated with the butanol threshold test and mucociliary transport was assessed by saccharin transit time (STT). Postoperative butanol threshold scores were significantly reduced (p < 0.01), and the changes were more profound in severer forms of paranasal sinusitis as graded by ostiomeatal-unit computed tomography. The mean preoperative STT (27 min) which was significantly longer than that of controls (12 min) was significantly reduced 1, 6 and 12 months following FESS (p < 0.01). The results suggest that impairment of olfaction and mucociliary transport in chronic paranasal sinusitis may be significantly improved following FESS.

Adult↗

[Study on the families' participation need for women in labor].

This study was done to suggest basic modifications in the present situation for the family of women in labour which is a separation management method. The study design was a descriptive study. The number of the subjects were 80. They were husbands, mothers in law, and mothers of women in labour who were full term and for whom there were no complications, either for the mother or the fetus. Data collection was done with a structured questionnaire which was analyzed using frequencies. The results were as follows, 1. Most of the subjects (95.0%) wanted to participate in the labour process. 2. The subjects wanted to support the women in labour by way of encouraging (95.0%), consoling (95.0%), listening to (75.0%), praying with (68.8%), hand holding (97.5%), stroking (63.8%), helping with respiration control (50.0%), maintaining relaxation (46.3%), changing position (58.8%), and illustration (58.8%). 3. The subjects answered that they expected their participation to have the effect of an easier labour course (52.5%), security for the women in labour (95.0%), and providing a better relationship between the women in labour (66.3%) and the new baby (55.0%). 4. The priority of the response as to who is the best supporter was husband, and mother of the women in labour in that order. It can be concluded that nurses maintained a management method which ignored the needs of the families of women in labour. If given consideration is to be given to these subjects, future programs should initiate ways to let the families participate in the labour process.

Clinical Nursing Research↗

Multistep photorefractive keratectomy for high myopia.

Nineteen human myopic eyes exceeding -8.00 D underwent multi-step excimer laser photorefractive keratectomy (PRK) with 6-month follow up. We performed two or three step PRK at the same time according to the amount of myopia present. The preoperative refraction ranged from -8.87 D to -16.99 D (mean -12.28 D). The mean attempted correction was 7.83 D. Six months after surgery, the mean refraction was -2.23 D. Keratometry demonstrated stable flattening of the cornea, and pachometry showed central cornea thinning. Seventeen eyes had clear or trace corneal haze. Above results showed multi-step PRK is a safe and relatively efficient procedure for correction of high myopia, but long-term follow up will be necessary to determine the stability of this procedure.

Adult↗