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Biomedical subjects

Y Revillon

Publications and source records attributed to Y Revillon.

At least 109 records · Page 6Linked to original sources

[Retroperitoneal hamartoma. Apropos of 6 cases].

Retroperitoneal hamartoma is an exceptional, benign, malformative tumor (1, 2% among retroperitoneal tumors in children). The authors report 6 cases which have been observed at the C.C.I. (Hôpital des Enfants Malades. Paris) for a 15 years period. This tumor has been revealed, generally in 3 years old children, by various clinical pictures. Echography can confirm the liquid contents of the tumor and her retroperitoneal sit. Surgical but non aggressive complete remove leads to recovery without any sequela.

Child↗

[Retrospective study of 56 congenital diaphragmatic hernias. Prognostic factors, therapeutic deductions].

Fifty-six neonates were treated for congenital diaphragmatic hernia (48 left and 8 right) in our intensive care unit from 1972 to 1980. Because of the high mortality, we studied the factors which could predict the outcome. Early onset of symptoms (before the 2nd hour of life) and low post-ductal shunt (PAO2/FiO2 less then 15) after the 3rd postoperative hour appear to be signs of poor prognosis. Our present attitude is early surgical procedure, controlled ventilation with a FiO2 1 with Pancuronium, prevention of pneumothorax and different use of pulmonary arterial vasodilatators.

Hernia, Diaphragmatic↗

[Hyperlucent pulmonary areas caused by stenosis or bronchial atresia in children].

From 1976 to 1979, 4 congenital bronchial abnormalities (1 stenosis, 3 atresias) have been observed and cured at Hospital des Enfants Malades Paris. The pulmonary distension with impaction of mucous secretion evocates the diagnosis. The bronchography shows the stenosis of the atresia. The pulmonary function testing confirms the hypoperfusion and the hypoventilation. The surgical indication is done in order to prevent complications and to suppress the compression of the lung. The results are good. The pulmonary testing function is correct long while after the operation. The authors discuss the surgical indication in function of the increasing of the lung.

Bronchi↗

Quantitative analysis of anorectal pressures in Hirschsprung's disease.

Anorectal motility was investigated in 146 children with Hirschsprung's disease and 89 normal control subjects. Pressures were recorded in the rectum and anal canal at rest and during rectal distention. The rectoanal inhibitory reflex was absent in all but four patients. Intraluminal rectal pressure was higher than normal (16.5 vs. 14.6 cm H2O, P less than 0.03), with more frequent (41 per cent vs. 18 per cent, P less than 0.01) pressure waves. In the upper anal canal, there were more frequent (62 per cent vs. 18 per cent, P less than 0.001) spontaneous variations of pressure of lower frequency (9.5 vs. 12.8 cycles/min P less than 0.001) and greater amplitude (5.2 vs. 3.6 cm H2O, P less than 0.001) than normal. The rectoanal contractile reflex occurred in 47 per cent of the patients but in only 21 per cent of the control subjects (P less than 0.001). Aganglionosis was associated with the presence of a rectoanal inhibitory reflex in three patients. This study confirms the value of anorectal manometry in diagnosing Hirschsprung's disease in a large group of patients, and demonstrates other abnormalities that may be useful in cases in which histologic and manometric data are in conflict.

Adolescent↗

[Primary intussuception of appendix (author's transl)].

A 2 years old female presents abdominal pain and rectal bleeding roentgenological and endoscopic investigations lead to the diagnosis of intussusception of the appendix. Surgically resected, the clinical course was uneventful and the patient promptly discharged. Primary intussusception of the appendix is a rare event (less than 200 cases recorded since 1858). The particularity of it, according the age of the patient, the clinical symptoms, and the endoscopic diagnosis are emphasized.

Appendix↗

[Neonatal primary chronic adynamic bowel (author's transl)].

Three cases of a primary disorder of intestinal motility which was responsible for neonatal functional intestinal obstruction are reported. This serious condition affected the small intestine and the colon and was difficult to treat. Early operation and prolonged intravenous alimentation was necessary. It is distinct from Hirschsprung's disease because of the presence of ganglion cells and because of the abnormalities of the myenteric plexus on silver staining. However the clinical symptoms and the decreased intraparietal cell V.I.P. concentration in pathological areas are similar in both conditions.

Female↗

[Pulmonary hypertension and fetal circulation after severe congenital diaphragmatic hernia (author's transl)].

The authors present four new born with severe anoxemia after congenital diaphragmatic hernia repair. In three babies' hypoxemia was present from birth. Cardiac catheterization revealed pulmonary hypertension, resulting in a state of fetal circulation. Tolazoline produced an improvement in oxygenation, but became secondary ineffective. In one case ductus arteriosus was occluded during cardiac catheterization, after which immediate improvement in peripheral oxygenation was seen. Ligation of the patient ductus arteriosus was proposed in that case. In the fourth infant, hypoxemia developed secondary and was successfully treated with tolazoline. It is suggested that ligation of the patient ductus arteriosus and administration of pulmonary vasodilatators are both effective in improving oxygenation, in patients who may die an anoxic death after repair of a severe congenital diaphragmatic hernia.

Ductus Arteriosus, Patent↗

[Constipation in the infant (author's transl)].

The authors studied 102 cases of constipation in children. 76 of them went through a protocol of investigations : clinical, psychological, radiological and manometric. The authors suggest that so-called functional constipation is more often organic than is commonly thought.

Adolescent↗

[65 orthotopic transplantations of the liver in the pig. Clinical and laboratory results (author's transl)].

The authors report the clinical and laboratory results of 65 orthotopic allotransplantations of the liver in the pig. The operative mortality (8 cases) was nil in the last 23 transplantations. Vascular filling without blood transfusion, blood alkalinisation and precautions to avoid hypothermia, seem essential to reduce early mortality. The various causes of secondary mortality are studied, using certain preventive measures. Thus, deaths due to gallbladder or hepatic ischemia have become rare by conserving end-to-end anastomosis on the hepatic artery and taking certain precautions. The grafts were rejected only in incompatible pigs in the SLA system, but were not rare in this group (13/43) and sufficient to cause death in one case out of two. Gastric ulcers were frequent, even after vagotomy, but vagotomy protects fairly well against ulcer hemorrhage. However, ulcers almost always accompany a disease which is alone sufficient to cause death. Cholangitis appears less frequent after cholecysto-jejunal anastomosis on an excluded omega loop. The mortality from extra-hepatic causes was severe (12 cases), in particular due to mechanical complications at the level of the small intestine. Laboratory analyses showed a definite rise in SGOT transaminase levels and, above all, alkaline prosphatase levels in cases of rejection compared with cases of biliary obstruction or hepatic necrosis.

Animals↗