Biomedical subjects
Publications and source records attributed to Y Popowski.
As the classical surgical treatment of squamous cell esophageal carcinoma is associated with poor 5-year survival rates and high operative mortality, radiotherapy and chemotherapy are being used as adjuvant or alternative primary treatments. The authors present their view on several therapeutic approaches and describe their irradiation technique.
Tolerance of normal tissues limits the radiation dose which can be safely delivered to tumors especially for gastro-intestinal cancers. Intraoperative radiotherapy is a specialized technique for treating infradiaphragmatic and deeply located tumors allowing to deliver a high dose to the tumor while avoiding surrounding normal tissues which can be moved aside. The authors describe the technique and review indications and possibilities.