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Biomedical subjects

Y Ota

Publications and source records attributed to Y Ota.

At least 181 records · Page 10Linked to original sources
PubMed1984

[Surgical treatment of pulmonary atresia (PA) and critical pulmonary stenosis (PS) with intact ventricular septum (IVS)].

Patients with PA: IVS and critical PS: IVS tend to have hypoplastic right ventricles and tricuspid valves. There is a large range of hypoplasia, but the relationship between the size of the right ventricle cavity and the size of tricuspid valve ring were found to be statistically significant. Pulmonary valvotomy alone is usually not adequate for the first stage operation and a systemic-pulmonary shunt procedure often become necessary. Use of PGE1 improved the overall clinical prognosis of these patients. The appropriate operative method for the second stage operation should be determined by measuring right ventricle volume and evaluating the degree of hypoplasia of the right ventricle, tricuspid valve and pulmonary artery. In three patients with right ventricle and tricuspid hypoplasia, we performed the Glenn procedure in addition to right ventricle outflow reconstruction and obtained good surgical results.

Child, Preschool↗
PubMed1983

Decrease in the zinc turbidity test values in patients with liver cirrhosis: a possible indicator for impending hepatocellular carcinoma.

A retrospective investigation of 21 cases of hepatocellular carcinoma with liver cirrhosis presumably of viral origin revealed a significant fall in the value of the zinc turbidity test from 15.5 +/- 6.9 (mean +/- SD) at 1 year to 11.2 +/- 2.5 units at 6 months before the discovery of the carcinoma (p less than 0.05), and a return to 16.8 +/- 7.2 units one month after the diagnosis (p less than 0.05). The values at 6, 2 and 1 month before the diagnosis were significantly lower than that for 120 control cirrhotics without hepatocellular carcinoma at 16.3 +/- 7.2 units (p less than 0.05). The fall in value occurred before or concurrently with a rise in the alpha-fetoprotein level in three patients, in whom it has been determined serially. Based on the results obtained, the decrease in the zinc turbidity test value may be used as an indicator for impending hepatocellular carcinoma in patients with liver cirrhosis.

Adult↗
PubMed1983

[Surgical treatment of total anomalous pulmonary venous connection].

Surgical experience of 70 patients with TAPVC between 1966 and 1982 were reviewed. Their age ranged from 2 days to 13 years. Fifty-two patients (74%) were below 6 months of age, 36 (51) below 3 months and 17 (24%) were neonates, respectively. Thirty-seven patients (56%) were with supracardiac type, 14 (20%) were with cardiac type and 12 (17%) were with intracardiac type. Results of operation below 6 months of age were unsatisfactory. Only 10 patients including 3 neonates out of 52 survived. However, 16 of 18 patients over 6 months of age survived. Early referral and emergency intracardiac repair is important in small babies as well as precise operation and fine bypass technique. Patients with supersystemic pulmonary hypertension immediately after surgery showed poor prognosis. Long-term results with 26 survivors were satisfactory. Eighty-one % of them showed sinus rhythm and %LVEDV and LVEF were within normal range in 6 patients investigated. In recent years, surgery without angiocardiography is recommended as the diagnostic ability of UCG developed. However, care must be taken as to some rare complicated pulmonary venous connection and associated cardiac anomaly such as VSD. Also, it should be recognized that pulmonary venous beds in neonates and early infancy demonstrated various degree of mascularization , medial hypertrophy and endothelial cell proliferation in intraacinar pulmonary veins. They were more marked in cases with intracardiac type TAPVC .

Adolescent↗
PubMed1982

Homologous control sites and DNA transcription starts in the related argF and argI genes of Escherichia coli K12.

The argF and argI genes code for similar proteins able to assemble into hybrid isoenzymes and are therefore thought to share a common origin. We show here that the nucleotide sequence of the promoter and operator regions of these two genes are highly homologous. DNA regions preceding the control sites also present significant homologies. The results support the notion of divergent evolution of the two genes from a common ancestor. Like argE and argCBH , argF and argI are controlled by a repressor molecule recognizing a family of similar operator sites. Attenuation appears to play no role in this regulation.

Base Sequence↗