Search PubMed⌕ Search

Biomedical subjects

Y Oki

Publications and source records attributed to Y Oki.

At least 145 records · Page 8Linked to original sources
PubMed1982

[Breeding and rearing of Japanese field voles (Microtus montebelli Milne-Edwards) and Hungarian voles (Microtus arvalis Pallas) as new herbivorous laboratory animal species].

Microtus species are very useful as experimental small animals with herbivorous characteristics. In this report, to approach establishment of the use of Japanese field voles (M. montebelli) and Hungarian voles (M. arvalis) as experimental animals, the biological characteristics, breeding methods and reproductive performance of these animal species were comparatively investigated. The number of chromosomes of M. arvalis is 12n = 46, differing from those of M. montebelli, 2n = 30. The breeding and reproduction of the Microtus species were relatively easily accomplished in the laboratory, by giving high fiber-containing rations. These animals prove to be polyestrous and showed postpartum estrous on the day of parturition. In the breeding by the continuous mating of the same pair, there was little or no delay in implantation due to lactation, especially in M. arvalis resulting in continuous birth at intervals of 20 to 21 days. On examination of vaginal smears, Japanese field voles (M. montebelli) did not show any definite pattern whereas 23 out of 30 voles from Hungary (M. arvalis) examined showed 6- to 18-day cycles. There were remarkable differences between the Japanese voles and the Hungarian voles, both biologically and reproductively.

Age Factors↗
PubMed1980

Diabetic syndrome in the Chinese hamster induced with monosodium glutamate.

Neuronal necrosis in the arcuate and ventromedial hypothalamus regions is easily induced in 1-day-old Chinese hamsters by the administration of monosodium glutamate (MSG). New-born Chinese hamsters injected with MSG showed no sign of obesity, even when grown up, but apparently developed a diabetic syndrome.

Animals↗
PubMed1976

Production of immunoglobulins by tumor cell lines from avian lymphoid leukosis.

Two avian lymphoma cell lines, 1104-X-5 and 1104-B, were examined for ability to produce immunoglobulin. They were found to produce and release the components of immunoglobulins related to IgG and IgM. The analysis of sucrose density gradient and gel electrophoresis suggested that these components might consist of light chains and fragments of heavy chains.

Animals↗