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Biomedical subjects

Y Ohira

Publications and source records attributed to Y Ohira.

118 records · Page 7Linked to original sources
PubMed1979

Iron-deficiency anaemia and its effect on worker productivity and activity patterns.

The effects of iron-deficiency anaemia on workers productivity were studied in a tea plantation in Sri Lanka. The quantity of tea picked per day was studied before and after iron supplementation or placebo treatment. After one month's treatment significantly more tea was picked when the haemoglobin (Hb) concentration was increased by iron supplementation than when it was not. The degree of improvement was greater in more-anaemic subjects (those with concentrations of 6.0-9.0 g Hb/dl). The level of physical activity of anaemic subjects in their everyday environment was also recorded for four or 24 hours continuously both before and after treatment. After three weeks these levels was significantly greater in the iron-treated than matched placebo-treated subjects. The economic implications of increased work productively with iron treatment are evident, particularly in developing countries. These results also provide strong evidence for the clinical impression that people with iron-deficiency anaemia suffer from tiredness and weakness.

Adult↗
PubMed1979

Work capacity, heart rate and blood lactate responses to iron treatment.

Changes in haemoglobin (Hb), work performance, heart rate and postexercise blood lactate were studied in iron deficient, anaemic subjects for 16 d following total dosage infusion of iron dextran, i.v. (30-50 ml). Six adult men and 14 women were subjects with initial Hb levels of 6.6 +/- 0.6 g/dl (mean +/- SEM) for the iron treatment group (n=10) and 8.0 +/- 0.7 for the placebo group (saline infusion, n=10). Serum levels were 0.51 +/- 0.15 and 0.67 +/- 0.12 mg/l for the two groups, respectively. Haemoglobin and maximal work time increased significantly within 4 d after iron treatment and continued to increase up to 16 d. No changes were found in the placebo subjects. Heart rates at a given exercise intensity were lower in the iron treatment group than in control subjects who had the same Hb levels but had not been treated with iron. Post-exercise venous blood lactate was similar on succeeding days after iron treatment even though the subjects reached higher work loads. These results demonstrate the treatment of iron deficient, anaemic subjects with iron dextran results in improved work capacity within 4 d and a lower heart rate at a given work load after treatment which cannot be accounted for totally by the elevation of Hb concentration.

Adult↗
PubMed1977

Correction of water content and solute concentration in blood during hemoconcentration.

Eleven, healthy male students were subjected to an exhaustive bicyle ergometer exercise. Many parameters of hemoconcentration were examined in blood and urine samples which were collected before and after exercise. In an exercise lasting approximately 10 min, it was found that serum total protein (STP) would be a suitable parameter that could be used to calculate water content and actual decrease in water volume in blood due to exercise. Further, it is described how STP values before and during hemoconcentration can be used to eliminate the effect of plasma water loss from the determined values of various solute levels in blood.

Adult↗
PubMed1977

Hemoconcentration during isotonic handgrip exercise.

Three healthy males performed an intense isotonic handgrip ergometer exercise to exhaustion (approximately 10 min). Serum water, serum total protein (STP), and hematocrit were determined in the venous blood taken from the brachial veins in both exercised and nonexercised arms before exercise and 10 s, 1, 2, and 3 min after the termination of exercise. Although no sweat was observed, hemoconcentration occurred in both arms. The peak degree of water loss in the nonexercised arm, however, was delayed and lower than that in the exercised arm. Further, three healthy males were exposed to a sauna (76 degrees C) for 20 min to test the effect of sweating on hemoconcentration in the absence of physical movement. Venous blood was withdrawn from the forearm vein before the sauna, after 5 min in the sauna, and at 3 and 30 min during sitting recovery period. No hemoconcentration was observed during the course of the experiment.

Adult↗