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Biomedical subjects

Y Niimi

Publications and source records attributed to Y Niimi.

At least 127 records · Page 7Linked to original sources
PubMed1984

[A case of metrizamide encephalopathy with triphasic waves on EEG].

Metrizamide (Amipaque), a water soluble nonionic contrast medium has less toxic effect in comparison with other contrast media, and it is now widely used for myelography, cisternography, ventriculography and cerebrospinal fluid dynamic imaging. However, as the number of cases in which this medium has been utilized has gradually increased, incidents of toxic manifestations have been reported. Among these, there are a considerable number of case reports referring to metrizamide encephalopathy, but only a few authors reported the appearance of triphasic waves on EEG when they occurred. The authors experienced one case of metrizamide encephalopathy accompanied by frequent appearance of triphasic waves on EEG. A 31-year old male was admitted to our hospital with the complaint of right homonymous hemianopsia. At that time he was fully conscious and mentally alert. On CT, 39 mm X 45 mm partially enhanced isodense mass was revealed on the enlarged sella turcica. Laboratory findings showed high titer of prolactin (10200 ng/ml). Premedication of 100 mg phenobarbital i.m. was followed by the tomography of the sella turcica, using 8 ml of 250 mgI/ml metrizamide injected into L 3-L 4 subarachnoid space. Several hours after the examination, he complained of slight nausea and was kept in bed with his head placed in an elevated position. The next morning, he was found to be in a drowsy state. He was disoriented and could not respond adequately to questions asked. His naming of daily necessities was also poor, although he knew how to use them.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1983

[Trial equipment to measure skin conductance, based on the recommendations of The Society for Psychophysiological Research].

It has been recommended by The Society for Psychophysiological Research (USA) that skin conductance should be recorded by the application of constant voltage 0.5 V across the electrodes, and the resultant current should be measured by the amplification of potential across a small resistor in series with the skin. A simple and inexpensive circuit has been recommended for this purpose. However, we cannot afford the same circuit in Japan, since the reference diode LM 113 T is not available. A Japanese version for this purpose is proposed, with satisfactory results.

Galvanic Skin Response↗
PubMed1979

Twenty-four-hour secretory patterns of growth hormone, prolactin, and cortisol in narcolepsy.

Twenth-four-hour patterns of plasma GH, PRL, and cortisol concentrations concomitant with sleep stages were studied in four male patients with typical narcolepsy, aged 30--34 yr, and four normal subjects. All medications were withdrawn 2 weeks before the study. Blood was drawn every 20 min during a 24-h fasting period, except for the first sleep cycle of nocturnal sleep when samples were drawn at 5-min intevals. In all of the narcoleptics, a plasma GH peak associated with slow wave sleep at the nocturnal sleep onset was absent (n = 2) or markedly decreased (n = 2). The normal rise of PRL during sleep was present only in a narcoleptic, whereas a significant fall in plasma PRL concentrations occurred immediately after the sleep-onset rapid eye movement period and lasted 1--1.5 h in the remaining three patients. A sleep-onset rapid eye movement period occurred in all of the patients, and this abnormal phenomenon characteristic of narcolepsy was considered to be related to the suppression of GH release at the sleep onset and to the decrease of plasma PRL levels during the early part of sleep. In contrast, the normal circadian periodicity of cortisol secretion was evident in all of the narcoleptics.

Adult↗