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Biomedical subjects

Y Naveh

Publications and source records attributed to Y Naveh.

At least 73 records · Page 4Linked to original sources
PubMed1979

Neurological sequelae of septic meningitis. A follow-up study of 65 children.

Seventy-two children who survived septic meningitis were reevaluated after 3 to 11 years. Thirty-four (52%) of 65 children were found to have neurological sequelae. Of the 34, 15 had major sequelae and 19 showed evidence of only minimal brain dysfunction--namely, hyperkinetic behavior, organic learning disturbances and minor motor disabilities. Acute-phase findings that were significantly associated with the rate of neurological sequelae were age, time between onset and admission, seizures, spinal fluid glucose level and the number of polymorphonuclear cells. In view of the high frequency of late neurological sequelae, it is advisable that children who survive septic meningitis have long-term follow-up in order to detect evidence of minimal brain dysfunction. An early diagnosis will help in proper management.

Adolescent↗
PubMed1978

Urinary tract infection presenting with jaundice.

Jaundice was the presenting feature in an 8-year-old girl suffering from urinary tract infection (UTI) due to Escherichia coli. The jaundice cleared with the cure of the infection. The mechanisms of jaundice complicating UTI are discussed, and the importance of urine culture in infants and children with jaundice is stressed.

Child↗
PubMed1977

Rifampicin therapy in shigellosis in infancy.

Eleven infants aged 1-2 years suffering from shigellosis associated with Shigella flexneri type 6 were treated with rifampicin. All were initially treated with antimicrobial drugs to which Sh. flexneri was shown to be sensitive, but without effect. Rifampicin was effective in curing gastrointestinal symptoms and eradicating the bacilli in all infants in 5 days. The drug was given in a dose of 10-12 mg/kg per day divided into two equal parts, for 7 days. No untoward side effects were observed. Our experience should encourage the use of this agent in controlling outbreaks of shigellosis and in curing resistant Shigella spp. infections where other antimicrobial agents prove to be inefficient.

Dysentery, Bacillary↗
PubMed1976

Familial imperforate anus.

A boy, 2 years 5 months of age, was admitted for examination and was found to be mentally retarded. He had a history of low birth weight, covered anus, and perineal fistula. Investigation revealed ventricular septal defect and persistent left superior vena cava, left upper lobe atelectasis, hand and foot anomalies, agenesis or nonfunctioning right kidney and large left kidney with double pelves and double ureters, and large sigmoid colon. Family history revealed consanguineous parents and a mentally retarded elder sister who had anorectal atresia with introital fistula and perineal ectopic stenotic anus. This family demonstrates two extremes of the same syndrome, most probably inherited as an autosomal-recessive entity.

Abnormalities, Multiple↗
PubMed1976

Pfeiffer syndrome: report of a family and review of the literature.

A 5-year-old boy and his father with Pfeiffer syndrome are described. They had acrocephaly, hypertelorism, antimongoloid slant of the palpebral fissures, protrusion of the eyes, large and broad nose, small mandible, irregularly placed teeth, additional upper canine, high-arched palate, partial syndactyly of fingers and toes, brachydactyly of toes, valgus deformity of hypertrophied triangular great toes, broad phalanges of the great toes and broad first metatarsals, accessory epiphyses lateral to the interphalangeal joint of the great toes, and normal intelligence. To our knowledge, this is the first family in which the syndrome is almost totally confined to the head and feet--it spares the upper limbs except for partial skin syndactyly between the fingers--and the third family showing inheritance through three successive generations suggesting an autosomal dominant mode of inheritance. The published papers are reviewed and the clinical and x-ray signs are tabulated.

Acrocephalosyndactylia↗
PubMed1975

Eggshell aspiration in infants.

Two infants inhaled eggshell fragments. The first aspirated a small fragment into the upper part of the trachea and resuscitation attempts resulted in descent of the foreign body to the right lower lobe bronchus. Two attempts at bronchoscopy were unsuccessful and spontaneous disintegration occurred. The second infant aspirated an eggshell fragment to the entrance of the larynx where it was removed by laryngoscopy. Laryngeal or tracheal foreign body in infants under 1 year of age are rare, and the diagnosis and removal are difficult.

Animals↗
PubMed1975

Endocarditis caused by Rhodotorula successfully treated with 5-fluorocytosine.

A 7-year-old boy suffering from aortic regurgitation and mitral stenosis and regurgitation was admitted with endocarditis caused by Rhodotorula pilimanae and was treated successfully with orally administered antifungal agent, namely 5-fluorocytosine (5-FC). A dose of 100 mg per kg body weight, divided into four equal parts, was prescribed. After a prolonged febrile period his temperature dropped to normal on the fourth day of 5-FC therapy. Review of the published reports disclosed few cases of endocarditis due to Rhodotorula spp. and this case seems to be the first treated with 5-FC. Follow-up in one year, after discharge from the hospital, revealed no evidence of relapse.

Administration, Oral↗
PubMed1975

Ultrastructural features of mast cells in systemic mastocytosis.

A 3-year-old boy with systemic mastocytosis has been observed since the age of 4 months when he was first diagnosed as suffering from urticaria pigmentosa. Involvement of skin, liver, spleen and bones was observed. The electron microscopy of skin and liver revealed varied alterations in the morphology of mast cells. The most important findings were irregularly-shaped cells and unusual long and interdigitated cytoplasmic villi, with consequent aggregation of mast cells which was more prominent in the dermis. Proliferation and accumulation of mitochondria in one part of the cell and deeply indented nuclei were frequent. The problem, whether the morphological changes encountered--especially the complex interdigitation of villi--should be interpreted as a sign of expected neoplastic development, is discussed.

Bone and Bones↗