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Biomedical subjects

Y Nako

Publications and source records attributed to Y Nako.

22 records · Page 2Linked to original sources
PubMedDate not supplied

Electrogastrography in neonates.

We recorded the electrical signals from bipolar electrodes placed on the abdomen of 7 adults and 10 newborn infants. Data were analyzed by visual inspection and by a wave analysis computer program with a fast Fourier transform. Waves of 3 cycles/min were recorded in adults, and similar 3 cycles/min waves were recorded in infants as well. The percentage of time of 3 cycles/min waves was lower in neonates (13.8% +/- 10.8%) than in adults (57.9% +/- 27.8%) (p < 0.01). Only an electrocardiogram superimposing the flat baseline was recorded in the remaining recording time. Spectral analysis confirmed the validity of the visual analysis, showing clear peaks at 0.05 Hz only when 3 cycles/min waves were visually present and motion artifact was absent. The electrode positions where percentage of time of 3 cycles/min waves was greatest were different for newborns and adults. There was no significant difference in the mean amplitude of the waves between groups. These facts indicate that the electrogastrogram of neonates is different from that of adults in terms of best electrode positions and percentage of time of 3 cycles/min waves.

Adult↗
PubMedDate not supplied

Successful interferon therapy in a neonate with life-threatening Kasabach-Merritt syndrome.

We report a neonatal case of severe, life-threatening Kasabach-Merritt syndrome that was successfully treated with interferon-alpha: This patient had a huge hemangioma of the right leg and a general bleeding tendency. Although the condition initially responded to steroid and radiation therapy, after a relapse, no therapy including steroids, radiation, aspirin, and dipyridamole was effective. Because of severe thrombocytopenia and extension of the hemangioma to the pelvic region, surgical intervention was not indicated. Interferon-alpha therapy was started on day 61 of life. During the therapy the platelet counts increased by more than tenfold and reached the normal level in a month. The size of the hemangioma dramatically decreased. The administration of interferon-alpha might be indicated as a therapy for severe, life-threatening Kasabach-Merritt syndrome, especially when there is resistance to steroid or radiation therapy.

Adult↗